以电阀值测定性病患者排障碍与周边经病变之相关性

以電流閥值測定女性糖尿病患者排尿障礙與周邊神經病變之相關性 李偉嘉 1、黃國皓 2、余宏政、陳淳、吳惠培 3、戴東原 3 台灣大學附設醫院泌尿部, 3內科部新陳代謝科 1台北市立和平醫院，2忠孝醫院泌尿科 VOIDING DYSFUNCTION IN FEMALE DIABETIC PATIENTS: RELATIONSHIP TO PERIPHERAL NEUROAPTHY DETECTED BY CURRENT PERCEPTION TEST Wei-Chia Lee1, Kuo-How Huang2, Hong-Jeng Yu, Jun Chen, Hui-Pei Wu3, Dong-Yuan Dai3 Department of Urology and3 Internal Medicine, National Taiwan University Hospital, Department of Urology, 1Taipei Municipal Hoping Hospital and 2Zhongxiao Municipal Hospital Taipei City Purpose: The possible relationship between voiding dysfunction and peripheral neuropathy was investigated in a cohort of women with diabetes. Materials and Methods: We conducted a cross-sectional study on 180 female patients in diabetic clinic over 6 months. Patients with possible confounding factors such as cystocele, cerebral vascular accident and history of major pelvic surgery were excluded. Of 180 diabetic women, 57 patients had ever received the current perception test, uroflowmetry and measurement of post-void residual. The current perception thresholds were determined for 5Hz, 250Hz, and 2000 Hz at the middle finger and great toe. Results: Based on a cutoff value of percent residual volume of greater than 25%, or a post-voided residual urine of >100 ml, or a total volume of >500ml, 15 persons were considered as voiding dysfunction and 42 persons did not. The results provided good discrimination between the voiding dysfunction and control groups at 5Hz(118.8±63 vs. 67±7.0, p=0.002), 250Hz (163±61.2 vs.128.2±22.2, p=0.05) in the foot. There were no significant differences of current perception measurements at all frequency between the voiding dysfunction and control group in the hand. Age showed no significant difference in these patients (61±2.5 vs. 62±1.5, p=0.7). Conclusions: According to the evoked sensations of neurometer, our data suggested small fiber damage in the toe should be correlated to the voiding dysfunction in diabetic women.