近年发表论文

姓名 段树民 性别 男 国籍 中国 工作单位、职务：中国科学院神经科学研究所 研究员，副所长；中国科学院院士，神经科 学国家重点实验室主任，全国政协委员 单位电话 021-54921818 传真 021-54921735 电子邮箱 shumin@ion.ac.cn 学历 1978 年 02 月至 1982 年 08 月 蚌埠医学院，医疗系 医学 学士 1982 年 09 月至 1985 年 08 月 南通医学院 生理学 硕士 1988 年 10 月至 1991 年 03 月 日本九州大学医学部 生理学 博士 工作简历 1985 年 09 月至 1988 年 09 月 南通医学院航海医学研究所 助教，讲师 1992 年 01 月至 1994 年 02 月 中国科学院上海脑研究所 博士后 1994 年 03 月至 1995 年 03 月 南通医学院航海医学研究所 副研究员，所长 1995 年 04 月至 1996 年 04 月 日本九洲大学医学部 世川医学奖学金特别研究员 1996 年 07 月至 1997 年 11 月 美国夏威夷大学 博士后 1997 年 12 月至 1999 年 12 月 美国加州大学旧金山分校神经科 博士后 2000 年 01 月至今中国科学院神经科学研究所 研究员 2007，9 月：神经科学国家重点实验室 主任 2007 年 11 月 中国科学院 院士 2008 年 3 月 全国政协委员 2008 年 11 月 发展中国家科学院（第三世界科学院, TWAS）院士 2009 年 3 月 中国科学院神经科学研究所 副所长 学术任职 编委： 《Journal of Neurophysiology》, 《Neurobiology of Disease》， 《Glia》， 《Hippocampus》 《中国科学 C 辑：生命科学》 获奖： 2007 年上海市科技精英 2008 年 何梁何利奖 近年发表论文： Duan S, Anderson CM, Stein BA, Swanson RA, Glutamate induces rapid upregulation of astrocyte glutamate transport and cell-surface expression of GLAST. J Neurosci 19：10193-10200 (1999) Swanson R.A., Duan S., Regulation of glutamate transporter function (Review). Neuroscientist, 5: 280-282 (1999) Duan S, Cooke IM, Selective inhibition of transient K+ current by La3+ in crab peptide-secretory neurons. J Neurophysiol 81:1848-1855 (1999) Duan S, Cooke IM, Glutamate and GABA activate different receptors and Cl (-) conductances in crab peptide-secretory neurons. J Neurophysiol 83: 31-37 (2000) Anderson CM, Norquist BA, Vesce S, Nicholls DG, Soine WH, Duan S, Swanson RA. Barbiturates induce mitochondrial depolarization and potentiate excitotoxic neuronal death. J Neurosci. 22:9203-9209.（2002） Xiang Y, Li Y., Zhang Z., Wang S., Yuan XB., Wu CP, Poo MM and Duan S*, Nerve growth cones guidance mediated by G-protein-coupled receptors. Nature Neuroscience, 5, 843 - 848 (2002) （全国百篇优秀博士论文） Duan, S, C M. Anderson, E C. Keung, K.Farrell, Y. Chen, and RA. Swanson. P2X7 Receptor-Mediated Release of Excitatory Amino Acids from Astrocytes. J Neurosci, 23: 1320-1328 (2003) Yuan X, Jin, M., Xu, X., Wu, CP., Poo, M., and Duan, S*. Signalling and crosstalk of Rho GTPases in mediating axon guidance. Nature Cell Biology , 5, 38 - 45 (2003) （全国百篇优秀博士论文） Wang, Z., Xu, N., Wu,CP., Duan, S*., and Poo, M. Bidirectional Changes in Spatial Dendritic Integration Accompanying Long-Term Synaptic Modifications. Neuron, 37: 463-472 (2003) Yang, Y., Ge, W., Chen, Y., Wu, CP., Poo, M., and Duan, S*. Contribution of astrocytes to hippocampal long-term potentiation through release of D-serine. PNAS, 100, 15194 – 15199 (2003) （2003 年中国医药科技十 大新闻） Zhang, J. Ye, C., Wu, CP., Poo, M., and Duan, S*. ATP Released by Astrocytes Mediates Glutamatergic Activity-Dependent Heterosynaptic Suppression. Neuron, 40, 971-982 (2003) Comment in: O Pascual and PG. Haydon, Synaptic Inhibition Mediated by Glia. Neuron, 40, 873-875 (2003) （全 国百篇优秀博士论文） Wang B, Xiao Y, Ding BB, Zhang N, Yuan X, Gui L, Qian KX, Duan S, Chen Z, Rao Y, Geng JG. Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity. Cancer Cell. 4:19-29 （2003）. Li, C., Wu, CP., Duan, S*, and Poo, M. Bidirectional Modification of Presynaptic Neuronal Excitability Accompanying Spike Timing-Dependent Synaptic Plasticity. Neuron，41, 257–268 （2004） Xu, H., Yuan, X., Guan, C., Duan, S., Wu, C., and Feng, L. Calcium signaling in chemorepellant Slit2-dependent regulation of neuronal migration. PNAS, 101, 4296-4301 (2004) Pan, P., Cai, Q., Lin, L., Lu, P., Duan, S*., and Sheng, Z. SNAP-29-mediated Modulation of Synaptic Transmission in Cultured Hippocampal Neurons. J. Biol.Chem. 280: 25769-25779 (2005) Xu X, Fu AK, Ip FC, Wu CP, Duan S, Poo MM, Yuan XB, Ip NY. Agrin regulates growth cone turning of Xenopus spinal motoneurons. Development. 132:4309-4316. (2005) Jin W, Ge WP, Xu J, Cao M, Peng L, Yung W, Liao D, Duan S, Zhang M, Xia J. Lipid binding regulates synaptic targeting of PICK1, AMPA receptor trafficking, and synaptic plasticity. J Neurosci. 2006 Mar 1;26(9):2380-90. Shen WH, Wu B, Dou Y, Zhang ZJ, Duan S* Rapid activity-induced synaptic maturation mediated by brain-derived neurotrophic factor. Neuorn, 2006, 50: 401-414（封面文章） Comment in: Atasoy and Kavalali，Presynaptic Unsilencing: Searching for a Mechanism. Neuron, 2006, 50:345-346 Ge WP, Yang XJ, Zhang ZJ, Wang HK, Deng QD, and Duan S* Long-Term Potentiation of Neuron-Glia Synapses Mediated by Ca 2+ -Permeable AMPA Receptors Science, 2006， 312, 1533-1537 （全国百篇优秀博士论文， 2006 年中国基础研究十大新闻） Lu W, Zheng BJ, Xu K, Schwarz W, Du L, Wong CK, Chen J, Duan S, Deubel V, Sun B. Severe acute respiratory syndrome-associated coronavirus 3a protein forms an ion channel and modulates virus release. PNAS, 2006, 103:12540-12545 Duan S*, Neary J, P2X7/P2Z receptors: properties and relevance to CNS functions (Invited review). Glia, 2006, 54:738-746. Ge WP, Duan S*. Persistent Enhancement of Neuron-Glia Signaling Mediated by Increased Extracellular K+ Accompanying Long-Term Synaptic Potentiation. J Neurophysiol. 2007, 97: 2564-2569 Yang W, Zheng C, Song Q, Yang X, Qiu S, Liu C, Chen Z, Duan S, Luo J. A three amino acid tail following the TM4 region of NR2 subunits is sufficient to overcome er retention of NR1-1a subunit. J Biol Chem. 2007, 282:9269-9278 Zhang X, Xu R, Zhu B, Yang X, Ding X, Duan S, Xu T, Zhuang Y, Han M. Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation. Development. 2007, 134:901-908. Zhou W, Ge WP, Zeng S, Duan S, Luo Q. Identification and two-photon imaging of oligodendrocyte in CA1 region of hippocampal slices. Biochem Biophys Res Commun. 2007 Jan 19;352(3):598-602. Chen G, Li HM, Chen YR, Gu XS, Duan S* Decreased estradiol release from astrocytes contributes to the neurodegeneration in a mouse model of Niemann-Pick disease type C. Glia. 2007, 55:1509-1518. Wang, C., Zhang, L., Zhou, Y., Zhou, J., Yang, X., Duan, S., Xiong, Z., Ding, Y.(2007) Activity-dependent development of callosal projections in the somatosensory cortex. J. Neurosci. 27: 11334-11342 Z-J Zhang, G Chen, W Zhou, A-H Song, W Wang, T Xu, Q-M Luo, X-S Gu, Duan S*, Regulated ATP release from lysosomes in astrocytes. Nature Cell Biol 2007, 9: 945-953. Liao CY, Li XY, Wu B, Duan S*, Jiang GB. Acute enhancement of synaptic transmission and chronic inhibition of synaptogenesis induced by perluorooctane sulfonate through mediation of voltage-dependent calcium channel. Environ Sci Technol. 2008 42:5335-5341 Zheng J, Shen WH, Lu TJ, Zhou Y, Chen Q, Wang Z, Xiang T, Zhu YC, Zhang C, Duan S, Xiong ZQ. Clathrin-dependent endocytosis is required for TrkB-dependent Akt-mediated neuronal protection and dendritic growth. J Biol Chem. 2008,283:13280-13288. Yu HM, Wen J, Wang R, Shen WH, Duan S, Yang HT. Critical role of type 2 ryanodine receptor in mediating activity-dependent neurogenesis from embryonic stem cells. Cell Calcium. 2008, 43:417-431. Li H, Chen G, Zhou B, Duan S*. Actin Filament Assembly by MARCKS- PI(4,5)P2 Signaling Is Critical for Dendrite Branching. Mol Biol Cell. 2008, 19: 4804-4813 Song AH, Wang D, Chen G, Li Y, Luo J, Duan S*, Poo MM. A selective filter for cytoplasmic transport at the axon initial segment. Cell. 2009, 136:1148-1160. “*”Corresponding or co-corresponding author. * 通讯作者 重要国际会议特邀报告: 1. Plenary Lecture: The 9th European Meeting On Glial Cells In Health and Disease. To be held in 2009, September 8-12, Paris, France 2. 3 rd Annual Canadian Neuroscience Meeting, to be held from May 24-27, 2009, Vancouver, Canada 3. Gordon Research Conference on “ Glial Biology: Functional Interactions Among Glia & Neurons”, March 15-20, 2009, Ventura, CA (USA) 4. Gordon Research Conference on “Neurobiology of Brain Disorder ”, August 24-29, 2008, Oxford, United Kingdom 5. Gordon Research Conference on“Molecular & Cellular Neurobiology ” , Jun 8-13, 2008, Hong Kong, China 6. Cold Spring Harbor Laboratory Meeting “Glia in Health & Disease”, July 17 - 21, 2008, Cold Spring Harbor (USA) 7. Gordon Research Conference on “ Glial Biology: Functional Interactions Among Glia & Neurons”, March 11-16, 2007, Ventura, CA (USA) 8. Gordon Research Conference on “ Excitatory Synapses and Brain Function” , June 10-15, 2007,Colby-Sawyer College in New London, New Hampshire (USA) 9. 2007 Gordon Research Conference on "Neurotrophic Factors", June 17-22, 2007, Salve Regina University in Newport, Rhode Island 10. Symposium in the 7th IBRO WORLD CONGRESS OF NEUROSCIENCE: Purine mediated neuron-glia interactions: physiological and pathological relevance (Chair). Melbourne, Australia, 12-17 July, 2007. 11. Plasticity of neuron-glia signalling, The 4th Congress of Federation of Asian-Oceanian Neuroscience Societies (FAONS), November 30 - December 2, 2006, Hong Kong 12. 10．Neuron-glia crosstalking in synaptic plasticity and neuronal signaling integrations. International symposium on Glial Activities in Neural Plasticity and Information Processing. Jan 2005, Tokyo 13. Gordon Research Conference (GRC), Glial Biology: Functional Interactions Among Glia and Neurons, March, 2005, Ventura, CA, USA 14. The 20th BIENNIAL MEETING of the International Society for Neurochemistry (ISN), Symposium: Glial cells as therapeutic targets for neurological disorders. Aug 2005, Innsbruck, Austria 15. Contribution of astrocytes to neuronal signaling processing, IBRO Symposium on Neural Plasticity, Development and Repair, April, 2004, Hong Kong. 主持重要学术会议: 1. Symposium in 10 th SCBA International Symposium: Development and plasticity of the Nervous system.（Co-chair） July, 2004, Beijing 2. First Chinese Symposium on Glia functions (Chair), Wuhan, China, Oct 17-18, 2005 3. Gordon Research Conference, Molecular & Cellular Neurobiology. (Section discussion leader: Synaptic Transmission II). Hong Kong, June 11-16, 2006 4. Symposium in the 7th IBRO WORLD CONGRESS OF NEUROSCIENCE: Purine mediated neuron-glia interactions: physiological and pathological relevance (Chair). Melbourne, Australia, 12-17 July, 2007. 5. Cold Spring Harbor Laboratory Meeting “Glia in Health & Disease” (Discuss leader), July 17 - 21, 2008, Cold Spring Harbor (USA)