超声介入腹腔神经节毁损治疗胰腺癌疼痛

第16卷第8期 2006年 4月 中国现代医学杂志 China Jourual of Modern Medicine Vo1．16 No．8 Apr．2006 文章编号： 1005—8982(2006)08—1 130—05 Analgesia on pancreatic carclnom a wRll cllemical destruction ● ’ ● - ■ ● l l ● - - ● ．' ’ ‘ ’ · · l - - -· 0t celiac ganglion Dy ultrasonic intervention WANG Tap，TIAN Fu-zhou，CAI Zhong—hong，LI Xu，SHI Li，CHEN Tap，CHEN Qi (Department of Generd Surgery,Chengdu Army,Chengdu，Sichuan 610083，P．R．China) Abstract： 【Objeetive】To detect the therapeutic effects of chemical destruction of celiac ganglion on patients tll pancreatic carcinoma with intractable pain．【Methods】97 cases with advanced pancreatic carcinoma accepted chemical destruction of celiac gan~ion——1 5 mL pure alcohol i~ection around celiac a~ery by ultrasonic inter— vention． nle varieties of VAS，sevtlm SP，B—EP and T—lymphocyte subtypes level were compared between pre—and post-therapy．【Results】Successful rate of puncture was 98．7％，with 1 loss．No serious complications such as trau- matic pancreatitis，pancreatic fistula，abdominal cavity hemorrhage or peritoneal infection in this study．VAS，sevtlm SP and 13-EP level significantly changed after treatment <0．01，P<0．05 and P<0．o1)，with complete relief rate 54．2％，partial relief rate 21．9％，inefficient ratel2．5％ and recurrent rate only 10．7％． rhe T—lymphocyte subtypes level remarkably increased when compared with that of pre—therapy <0．oa)．【Conclusion】This study suggests that chemical destruction of celiac ganglion by ultrasonic intervention proves to be highly safe， and can evidently relieve cancer pain of pancreas and improve the cellular immune level on patients with advanced pancreatic carci— nom a． Key words：ultrasonic intervention；analgesia chemical destruction；pancreatic carcinoma；celiac ganglion CI C number：R81 Document code：A 超声介入腹腔神经节毁损治疗胰腺癌疼痛 汪 涛，田伏州1，蔡忠红，李 (成都军区总医院全军普外 旭，石 力，陈 涛，陈 琪 中心，四川 成都 61 0083) 摘要：目的 探讨超声介导腹腔神经节毁损对胰腺癌痛患者的治疗作用。方法 97例胰腺癌痛患者采用 B超引导经皮穿刺，于腹腔动脉干根部旁侧注入无水乙醇15mL，实施腹腔神经节化学性毁损。对比观察治疗 前后疼痛的视觉模拟评分(VAS)、血清sP和 B-EP以及T细胞亚群水平变化。结果 97例中仅1例穿刺失 败，成功率98，7％，无严重并发症；VAS、血清sP和 B-EP与术前差异有显著性(P表

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