Making the science of cognitive fitness work for you
Putting It All
Together
Enrich Your Life,
Enrich Your Brain
your Brain
at work
About This Report
Your Brain at Work: Making the Science of Cognitive Fitness Work for You
has been developed as part of a nationwide workplace program co-sponsored by the
Mature Workforce Initiative of The Conference Board and The Dana Alliance for
Brain Initiatives with support from The Atlantic Philanthropies.
The Mature Workforce Initiative is committed to helping employers engage and develop
mature employees within the rapidly changing multigenerational workplace. Our evolving
work is validated by frequent interaction with our 2,000 member companies as we respond
to their emerging business issues. Funding for the Initiative is generously provided by
The Atlantic Philanthropies.
The Conference Board is one of the world's pre-eminent business membership and
research organizations. Best known for the Consumer Confidence Index and the Leading
Economic Indicators, The Conference Board has, for more than 90 years, equipped the
world's leading corporations with practical knowledge through issues-oriented research
and senior executive peer-to-peer meetings.
The Dana Alliance for Brain Initiatives is a nonprofit organization of more than
265 neuroscientists who are committed to advancing public awareness of the progress
and promise of brain research and to disseminating information about the brain in an
accessible fashion. The Dana Alliance, supported entirely by the Dana Foundation, does
not fund research or give grants.
The Atlantic Philanthropies are dedicated to bringing about lasting changes in the
lives of disadvantaged and vulnerable people through grant-making. Atlantic focuses on
critical social problems related to aging, disadvantaged children and youth, population
health, and reconciliation and human rights.
Your Brain at Work 1
introduction
Put your brain to work
and it will work for you
What you do every day matters to
your brain. The choices you make,
your level of physical and mental
activity, your social life, diet, and
sleep habits—all these things can
affect cognitive fitness: a state in
which we are performing well men-
tally, emotionally, and functionally.
Your Brain at Work connects the
latest research to practical sugges-
tions for incorporating healthy brain
habits at work and at home. Good
choices can help you maintain cog-
nitive vitality in every area and at
every stage of your life.
Because you are working, you’ve
already taken the first step. A brain
at work is a brain that works. The
mental and social stimulation of the
workplace help keep your brain fit.
If you already have a wellness or fit-
ness program at work, this material
can add a brain health component
to it, or become the basis for a new
wellness program. On your own, you
can use this booklet as a personal
cognitive fitness tool kit.
Your Brain at Work includes basic
brain facts, a readiness quiz to deter-
mine what sort of brain lifestyle
you’re living, chapters on brain
health, and an action plan to help
you use this information wisely and
well. Brain health is a lifelong com-
mitment, and it’s never too early to
begin. Or too late. Practicing cogni-
tive fitness will help you stay on top
of your game, on the job and off.
In this booklet, we are going to
show you how.
We’ve all seen the news: we can affect how our brains work.Neuroscience tells us that we can increase our chances
of maintaining our mental edge and functional independence
throughout our lives. How? By working to keep our brains fit the
way we work to keep our bodies healthy.
2 Your Brain at Work
contents
Table of Contents
3 Readiness Quiz
4 Meet Your Brain
If you don’t know your cerebrum
from your cerebellum, have no
fear
8 What Does It Mean to Be
“Brain Fit”?
It’s true after all: use it or lose it
12 Move Your Body
When you work out your body,
your brain benefits
16 Meet, Greet & Be Social
Your brain needs social
connections
20 Work Your Brain
They’re called brainteasers for a
reason…
24 Feed Your Brain
Food for thought: diet matters
26 Stress Management
Relax! It’s only your brain we’re
talking about
30 Sleep, Rest Well
To sleep, perchance to retain new
information
36 How Can You Put It All
Together?
Enrich your life, enrich your brain
40 Summary: It’s Never Too
Late or Too Early to Begin
41 An Action Plan for Brain
Health
43 Glossary
4
26
12 16
20 3024
8
Your Brain at Work 3
Readiness Quiz
Answer these questions, and read on to find out why your answers are
important, and where they put you on the continuum of brain health. At the
end of the book, you’ll get an action plan that will help you incorporate diet,
exercise, and cognitive stimulation into a healthier brain lifestyle.
1. How much did you move today? Include every time you were ambulatory,
from jogging on a treadmill to walking around your office. ____________
______________________________________________________________
______________________________________________________________
2. How many social interactions did you have today? Include contacts with
your co-workers. _______________________________________________
______________________________________________________________
______________________________________________________________
3. Did you practice any new skills on the computer at work today? Work a
crossword puzzle? Do an ordinary task in a new way? ________________
______________________________________________________________
______________________________________________________________
4. If you are like most people, you probably do three things at once. But do
you know what recent studies have revealed about multitasking? ______
______________________________________________________________
______________________________________________________________
5. Did you eat any blueberries today? Fish aside, do you know what foods
are brain-healthy? ______________________________________________
______________________________________________________________
______________________________________________________________
6. How much sleep did you get last night? Was it uninterrupted sleep? Do
you often feel drowsy during the day? _____________________________
______________________________________________________________
______________________________________________________________
your brain
4 Your Brain at Work
your brain
Meet Your Brain
Some of the brain areas involved in cognitive processes are shown
here (and described at right).
Credit information: Image courtesy NINDS/National Institutes of Health.
cerebral cortex
frontal lobes
cerebellum
temporal lobes
occipal lobes
parietal lobes
sensory areas
motor cortex
your brain
Your Brain at Work 5
If you don’t know your cerebrum from
your cerebellum, have no fear
In the past decade alone, neuroscience has revolutionizedour understanding of the normal structure and function-
ing of the brain, how it changes as we age, and what can
go wrong in neurologic or psychiatric disease states. At the
same time, the brain is truly one of the last frontiers in
biological science, still rife with mysteries about its inner
workings.
Cerebral cortex: the brain’s
heavily folded outer layer of gray
matter, critical to cognitive
processing
Sulci: the shallow grooves in the
cortex; the central sulcus divides
the two hemispheres
Gyri: the ridges on the cortex
Cerebellum: facilitates
movement, coordination, balance,
and posture, and appears to be
involved in some types of learning
Frontal lobe: controls higher
thought processes and executive
function
Parietal lobe: perceives and
interprets bodily sensations such
as touch, pressure, pain, and
temperature
Temporal lobe: involved in
memory processing and
interpreting sounds
Occipital lobe: seat of the
visual cortex, which detects and
interprets visual stimuli
Hippocampus: part of the brain
that developed early in
evolutionary history; involved in
learning and short-term or
working memory
Motor cortex: part of the
cerebral cortex that controls
movement
6 Your Brain at Work
your brain
What’s clear is that each of us has
a brain that is unique. The overall
anatomy and location of key brain
structures is similar across the
population, but the pattern of
connections among nerve cells —
the synapses by which brain cells
talk to one another — is the singular
product of our individual life
experiences.
Each of our brains, no matter our
age, is a work in progress. It
responds and adapts and literally
rewires itself in accordance with
what we put into it — what we learn,
what we say, what we do, how we
interact with others, and even what
we eat. Scientists call this “plastici-
ty.” It’s the reason we can affect
our cognitive function when we take
the steps to do so.
Take learning, for example. When we
learn something new, and we learn
it well, our brain literally creates a
particular pattern of synaptic con-
nections for that learning. It’s as if
the phone number of your boss or
the route to your parents’ house
stakes out its own piece of real
estate in the brain — but it’s more
of a highway than a building lot.
Each new experience we encounter,
if it is repeated often enough, will be
represented in the brain with its
own signature pathway of nerve
connections. These connections
interlink and may overlap with many
(sometimes many thousand) other
pathways that are in some way
associated with that experience.
This is why repeating something we
want to learn, or associating it with
other things that will jog our memo-
ry, can improve the “laying down”
and later recall of the thing we’re
trying to remember.
Synapses that don’t continue to be
activated fade away. If your boss’
number changes, or your parents
move, the associated neural real
estate will likely be up for sale, at
least after a while. This is the “use
it or lose it” concept.
Some things may be indelibly
carved into our neural circuits — like
real estate permanently designated
for a specific use. You may still
remember the phone number of the
home you grew up in, even if you
haven’t used it in years. So, too,
emotionally charged memories may
be especially strong and enduring.
Your Brain at Work 7
your brain
A classic example from the
annals of brain science
showing how experience can
shape the brain is a 2000
study performed on London
cab drivers,1 who have highly
refined abilities for navigating a
large, complex city. Using mag-
netic resonance imaging (MRI),
researchers at University
College, London, found that cab
drivers’ hippocampuses — part
of the brain involved in spatial
memory and navigation — were
significantly larger compared
with those of other people. The
longer the taxi driver had been
on the job, the larger his hip-
pocampus was.
A number of studies have docu-
mented changes in the part of
the brain’s motor cortex that
maps activity in the hand
among musicians who play
string instruments or the piano;
it is even possible to determine
what instrument an individual
plays by looking at the pattern
of structural change in the
motor cortex.2 Other studies
suggest that practicing a skill
in the mind’s eye only — visual-
izing a specific series of finger
movements, for example, rather
than actually performing them
— has a corresponding effect
on brain structure in the rele-
vant region.
Such studies have become
classic examples of how one’s
life experiences literally shape
and reshape the brain.
Drive a Cab,
Expand Your Brain
What Does It Mean to Be
“Brain Fit”?
Notes from the lab
Research studies in many coun-
tries have found four factors that
may predict maintenance of
cognitive function.
1. Increased mental activity
2. Increased physical activity
3. Increased levels of social
engagement
4. Control of vascular risk by:
a. Controlling weight
b. Monitoring cholesterol
c. Monitoring blood pressure
d. Not smoking
Your Brain at Work 9
brain fitness
Everyone knows what a fit body looks like, but fit brains,which don’t boast rippled muscles or six-packs, are
tougher to distinguish. Brain fitness is a state of mind in
which we are performing well cognitively and emotionally.
When we’re cognitively fit, we’re maintaining our mental
edge, staying sharp, aging successfully. Brain fitness is not
only the absence of disease, either Alzheimer’s or other types
of dementia; it is also the preservation of emotional and cog-
nitive well-being throughout our working years and beyond.
Your brain at work is in a win-win
situation. Any cognitive stimulation
you receive in your workplace is
like a daily workout for your brain.
And the more fit your brain is, the
better prepared you are likely to be
to cope efficiently with the daily
challenges of life and work.
Developing a healthy brain attitude
and lifestyle has benefits at every
stage of life, in virtually every aspect
of our lives. The sooner we begin,
the better, but we can reap the
benefits regardless of when we
start, just as physical exercise can
improve physical health at any age.
Whether you are in your 30s or your
50s or even older, you may be able
to improve your cognitive vitality.
It’s true after all: use it or lose it
10 Your Brain at Work
brain fitness
“If we maintain cognitive function over
time, then we are more likely to be
functionally independent.”
Marilyn Albert, Ph.D., Professor of Neurology and
Psychiatry, Director of Cognitive Neuroscience,
Johns Hopkins University School of Medicine
The basics of cognitive fitness lie in
fundamental healthy-brain practices,
such as physical activity, social
interaction, mental stimulation, a
brain-friendly diet, healthy sleep
patterns, and stress management.
Benefits from such practices range
from cellular and biochemical
changes at the level of neurons and
synapses to “whole-brain” changes,
such as denser neural networks or
more efficient neural processing.
These kinds of physiological alter-
ations may be manifested as
improved cognitive functioning —
better memory, faster learning,
greater attention and focus — and
as emotional well-being.
The bottom line is that a brain-
healthy lifestyle is a combination of
many factors, each of which has its
own benefits to the brain. When
combined, the benefits are likely to
be additive: The more brain-healthy
practices you follow, the greater the
benefits.
Of course, no one can guarantee
that adopting a brain-healthy
lifestyle will absolutely ensure good
cognitive health until your dying day,
but the potential benefits of shaping
up your brain are increasingly well-
documented. In the following pages,
we’ll show you how to put these
scientific findings to work for you.
The Fundamentals of
Cognitive Fitness
Your Brain at Work 11
brain fitness
Cognitive fitness is
a state of mind in
which we are
performing well
mentally, emotionally,
and functionally.
Attaining it entails
following healthy-
brain practices, such
as exercising the
mind and body,
staying socially
connected, eating
and sleeping well,
and managing stress.
physical
activity
social
interaction
mental
stimulation
diet
adequate
sleep
stress
management
What if simple exercise could boost
the rate at which your brain makes
new neurons? Columbia University
researchers have found provocative
evidence that structured aerobic exer-
cise does exactly that3 – and we’re
not just talking about rodents on a
wheel.
Neuroscientist Scott Small and his
colleagues put 11 adults through 40
minutes of aerobics four times a week
for 12 weeks, then measured blood
flow in the participants’ brains.
Small’s team wanted to know whether
the exercise would help generate new
neurons in the hippocampus (a
process called “neurogenesis”), as
had previously been shown to occur in
animals.
Since there’s no way to measure neu-
rogenesis directly in humans, the
researchers did a parallel study in
mice, examining their brains after they
were allowed to exercise freely for
two weeks (mice actually like exer-
cise). They found blood flow changes
in the animals’ brains that correlated
with the degree of neurogenesis that
had occurred. Then they compared
these changes to those in the
humans’ brains.
The patterns matched closely, convincing scientists that they were seeing the first surro-
gate representation of increased neurogenesis in the human hippocampus. What’s more,
the blood flow changes in the brain correlated with both cardiopulmonary and cognitive
fitness. Conclusion: increased blood flow to the hippocampus may trigger or support new
neuron growth, which in turn may improve learning.
Physical Activity
Move Your BODY!
Notes from the lab
Your Brain at Work 13
brain fitness
When you work out your body,
your brain benefits
If you haven’t yet heeded the message to get moving,here’s one more good reason to do so: Increasing your
level of physical activity is one of the best things you can do
for your brain. You don’t have to run a marathon or develop
Popeye-like muscles; even a half-hour of moderate physical
activity (think: walking briskly) will help. Strive for that
much every day.
Enhances memory and learning,
demonstrated by better perform-
ance on a range of cognitive
tests.
Improves mood and counteracts
depression. There is substantial
evidence for the antidepressive
qualities of regular aerobic exer-
cise, and government-funded
clinical trials are underway to
investigate exercise as a treat-
ment for depression, alone or in
combination with antidepressant
medications.
Enlarges blood vessels to pump
more blood and oxygen into the
brain.
Increases levels of brain-derived
neurotrophic factor (BDNF), a
growth factor that supports and
nourishes brain cells.
Ramps up the rate at which new
nerve cells are generated in the
hippocampus, and increases
the volume of the hippocampus.
Increases the number of glia,
brain cells that support neurons
and speed neural processing.
How Exercise Helps
The last few years have seen an explosion of scientific evidence for the brain
benefits of exercise, leaving little doubt that increasing physical activity is
Job No. 1 for everyone interested in maintaining cognitive function.
Studies in humans and animals have found that exercise:
14 Your Brain at Work
brain fitness
How much exercise is needed?
“There is increasing research in human
and animal studies to suggest that physical
activity and exercise will protect your mind
and brain throughout your lifetime.”
Art Kramer, Ph.D., Professor of Psychology,
University of Illinois, Urbana-Champaign
The answer continues to be debat-
ed, but most experts agree that
striving for at least 30 minutes of
moderate exercise daily, four or
more days a week, is sufficient to
improve brain health. Most human
studies on the brain benefits of
exercise have had people doing aer-
obic exercise for 45 minutes to an
hour, three or four days a week, but
it’s important to keep in mind that
any exercise is better than none.
If you can’t find an hour to devote to
it, think piecemeal: Start with three
10-minute walks over the course of
the day. Aerobic exercise such as
swimming, cycling, or brisk walking
that raises the heart rate for a sus-
tained period is best, probably
because it floods the brain with
oxygen-rich blood.
Your Brain at Work 15
brain fitness
Use work breaks or lunch
times to go for a walk.
If you work at home, walk
around the block.
Skip the elevator and take
the stairs.
Use commuting time to
practice deep breathing and
good posture.
Park your car a distance from
your workplace and hoof it.
Stand up and walk around
while talking on the phone;
you can also do leg lifts,
extensions, or arm curls to
work your muscles.
Visit co-workers in person
instead of phoning or
emailing.
Use the restroom that is
farthest from your desk.
No time in your workday for
working out?
Be creative.
Fit in a little exercise whenever you can,
even while at wo