妊娠期补充爱乐维的临床疗效观察

妊娠期补充爱乐维的临床疗效观察 [摘要] 目的 观察妊娠期孕妇补充爱乐维的临床疗效。 方法 将866例妊娠期孕妇随 机分为观察组440例和对照组426例，对照组正常合理安排妊娠期饮食及生活习惯，观察组 在对照组的基础上口服爱乐维，观察比较两组孕妇孕中期、孕晚期的血清叶酸水平及妊娠期 不良反应。 结果 观察组和对照组在孕中期和孕晚期发生妊娠高血压综合征(简称:妊高征) 分别为26例(5.9%)和63例(14.8%)，发生贫血症分别为13例(3.0%)和71例(16.7%)。 新生儿神经管缺陷观察组9例(2.0%)，对照组24例(5.6%);低体重儿观察组35例(8.0%)， 对照组85例(20.0%);心血管畸形观察组21例(4.8%)，对照组 44例(10.3%)。 结论 爱 乐维的应用应持续整个围妊娠期，但一定要根据孕妇自身的情况，合理地设计使用爱乐维。 [关键词] 妊娠期;孕妇;维生素;胎儿 [中图分类号] R977.2 [文献标识码] A [文章编号] 1674-4721(2013)07(a)-0072-02 Observation on the curative effect of Philharmonic dimension during pregnancy ZHANG Li-hua Shenzhen Far-East Women & Children Hospital of Guangdong Province，Shenzhen 518000，China [Abstract] Objective To observe the clinical effect of Philharmonic dimension during pregnancy.Methods 866 pregnant women were divided into observation group 440 cases and control group 426 cases randomly.Eating and living habits during pregnancy were arranged reasonably for control group.And Philharmonic dimension was administrated to the pregnant women in observation group on the basis of control group.Serum folic acid level and adverse reactions during pregnancy during pregnant metaphase and late pregnancy of two groups were observed and compared.Results There were 26 cases (5.9%) and 63 cases (14.8%) pregnancy-induced hypertension syndrome patients occurred in observation group and control group during pregnant metaphase and late pregnancy respectively;anaemia were 13 cases (3.0%) and 71 cases (16.7%);newborn neural tube defect were 9 cases (2.0%) in observation group and 24 cases (5.6%) in control group;infants of low-birth weight were 35 cases (8.0%) in observation group and 85 cases (20.0%) in control group;Cardiovascular abnormalities were 21 cases (4.8%) in observation group and 44 cases (10.3%) in control group.Conclusion The Philharmonic dimension should continue in the whole pregnancy.However，Philharmonic dimension shall be administrated reasonably according to the pregnant women’s own situations. [Key words] Pregnancy;Pregnant women;Vitamin;Fetus 维生素和微量元素是胚胎发育过程中不可缺少的营养物质，妊娠期孕妇合理补充维生 素和微量元素，可为新生儿的健康成长打下良好基础，达到优生优育的目的。然而维生素和 微量元素的补充也不是绝对安全的，过量补充反而有可能给胎儿带来不良后果。爱乐维含有 多种维生素、矿物质和微量元素，尤其适用于妊娠期孕妇。本研究选取2011年10月,2012 年10月本院接收的妊娠期孕妇为研究对象，研究妊娠期孕妇适量补充爱乐维的临床效果， 现报道如下。 1 资料与方法 1.1 一般资料 选取2011年10月,2012年10月本院妇产科接收的正常妊娠期孕妇866例，均为单 胎，年龄20,31岁，孕周5,40周。将所有孕妇随机分为两组，观察组440例，平均年龄 (24.5?3.8)岁，平均孕周(12.7?8.4)周;对照组426例，平均年龄(25.6?3.2)岁，平均 孕周(13.3?8.1)周。两组孕妇在年龄、孕周、饮食生活、妊娠合并症等方面差异均无统计 学意义(P>0.05)，且近期无自服钙剂及激素等药物史者，具有可比性。 1.2 方法 对照组孕妇正常合理安排妊娠期饮食及生活习惯，不额外服用其他任何药物。观察组孕妇在对照组的基础上口服爱乐维，一次1片，一日1次，与早餐同时服用。观察比较两组孕妇孕中期、孕晚期的妊娠不良反应及新生儿状况。 1.3 统计学方法 采用SPSS 13.0统计学软件处理数据，计数资料采用χ2检验，以P