《巩膜病学》一书出版

《巩膜病学》一出版 ? 628?眼科新进展2O06年8月第26卷第8期 RecAdvOphthalmolVo1.26N0.8August2006 用什么方法(如药物或基因治疗)来减少脂褐素的沉积,都是 一 些需要进一步研究的问.这些问题的解决将为从根本 上预防与治疗AMD提供巨大的帮助. 参考文献 1SeddonJM.ChenCA.Tlleepidemiologyofage-relatedITlaCU- lardegenerationlJ】.IntOphthalmo1C1tn2004;44(4):17- 39. 2邹海东,张暂,许迅,汪枫桦,张世杰.上海市静安区曹家渡街 道年龄相关性黄斑变性的患病率调查[J].中华眼科杂志2005; 41(1):15'19. 3mralampus-GrynaviskiNM,IamabLE,ClancyCMR,Sku— matzC,BurkeJM,SarnaT,eta/.Spectroscopicandmor- phologicalstudiesofhulnanretinalllpofusclngranules 【Jf,ProcNatlAcadSet啦l2003;100:3179-3184. 4KatzML,DreaCM,EldredGE,HessHH,Robi$onWGJr. Influenceofearlyphotoreceptordegenerationonlipofns- clnintheretinalpigmentepithelium[J],ExpEyeRes 1986;43(4):561—573, 5SchuttF,UeberleB,SchnolzerM,HolzF,K0pitzJ.Pro- teomeanalysisoflipofnscininhunlanretinalpigmenteI>- ithelialcellsIJ】,FEBSLett2002;528(1-3):217l_221, 6LorenzB,W_abbelsB,WegschetderE,HamelCP,Drexler W,PreislngMN.Lackoffundusautofluorescenceto488 nanometersfromchildhoodoninpatientswithearly-on. setsevereretinaldystrophyassociatedwithmutationsin RPE65【JJ.Ophthalmology2004;111:1585-1594. 7LinJ,ItAgaktY,Ben-ShabatS,NaknntshiK,SparrowJR. T1lebiosynthesisofA2E,afluorophoreofingretina,il卜 volvestheformationoftheprecursor,A2-PE,inthepho- toreceptoroutersegmentmembrane\3\.JBlolChem 2000;275:29354-29360. 8Be仆ShabatS,PartshCA,VollmerHR,ItagaktY,Fishkin N,NakanishiK,eta1.BiosyntheticstudiesofA2E,anla- JorfluorophoreofRPElipofusctnjJJ.JBJ01Chem2002; 2771718玉.7190. 9MataNL.WengJ,TravisGH,Biosynthesisofamajorltpofns- clnfluorophoreinmiceandhumanswithABCR-medtated retinalandmaculardegenerationjJJ.Proc?afIAcadSct UsA2000;97:7154-7159, 10BelmrryS,ZhongM,MoldayS,N-retlnyltdene-phosphatid- vlethanolamineisthepIferredrettnotdsubstrateforthe photoreceptor-spectficABctransporterABCA4(ABCR)[J], JBto/em2004;279(52):53972-53979, 11WengJ,MataNL,AzarianSM,q2zekovRT,BirchDG,Travls GH.InsightsintothefunctionofRimproteininphotorece13- torsandetiologyofStargardt'sdiseasefromthephenotype inabcrknockoutmicelJ】.Ce?1999;98:13-23. 12KimSR,FtshktnN,KongJ,NakanlshlK,A1ltkmetsR, SparrowJR.TheRpe65Leu450Metvariantisassociated withreducedlevelsoftheRPEllpofnsclnfluorophores A2Eandiso-A2EIJ】.Proc?a?AcadSc|U_sA2004;101: 11668-11672. ?????-?-????-?-?????-?-..?' 《巩膜病学》一书出版 由方严,魏文斌,陈积中教授主编的《巩膜病学》一书已由 国家科学技术部科技文献出版社出版.本书作者来自国内多 所医学院校,科研机构,全书各章节均为在巩膜疾病某一领域 有研究成果的学者及研究人员,根据本人的临床实践及临床 研究成果,并参考了大量的国内外文献撰写.本书介绍了包 括感染性巩膜炎,非感染性巩膜炎,巩膜外伤,巩膜扩张,巩膜 13DelortFC.Autofluorescencemethodtomeasuremacular pigmentopticaldenstttesfluorometryandautoflnores- cenceimaging[Jj.ArchBiochemBIophys2004;430(2) 156-162. 14DelortFC.Go~erDG.DoreyCK.Age-relatedaccumulation andspatialdistributtonofItpofnsclninRPEofnormal snbJectslJ】,InvestOphthalmolVtsSet2001;42:1855- 1866, 15SparrowJR,ZhonJ,Be仆ShabatS,VbllrnerH,ItagakiY, NakanlshlK,Involvementofoxidativemechanismsin blue-light-induceddamagetoA2E-1adenRPElJ】,Invest OphthalmolV1sSet2002;43(4):1222-1227. 16ShamsiFA.BoultonM,InhibltlonofRPElysosomaland antloxldantactivitybytheagepigmentllpofuscln[Jj, InvestOphtbalm01VtsSet2001;42(12):3041-3046. 17SparrowJR,ZhouJ,CaiB,DNAisatargetofthephoto- dynamiceff.ectselicitedinA2E-ladenRPEbybluelight illuminationlJj,InvestOphthalmolVtsSet2003;4412245- 2251. 18SuterM,RemeC,GrimmC,WenzelA,JaattelaM,Esser P.eta3,Age-re】atednqaculardegeneration,n1elipofuston componentN-rettnyl-N-rettnyltdeneethanolamtnede— tachesproapoPt0ticproteinsfrommltochondrlaandin ducesapoptostsinmammalianretinalpigmenteditheltal cells【JJ,J励e/n2000;275(50){3962s.9630, 19SparrowJR.BoultonM.RPElipofusctnanditsrolein retinalpathoblology[J].ExpEyeRes2005;80(5):595. 606. 20F|nnemannSC,LeungLW,Rodrtguez-BoulanE.Thelipo- fusctncomponentA2Eselectivelyinhibitsphagolysoso- maldegradationofphotoreceptorphospholtpldbythe retinalpigmentepttheltumlJJ.Pr0c?atJAcadSetU_sA 2002;99(6):3842-3847, 21SakaiN,DecaturJ,NakantshiK,EldredGE,Ocularage pigmentA2E:anunprecedentedpyridiniumbtsrettnotd lJ】.JAmChems0c1996;118:1559-1560. 22SparrowJR,ParishCA,mshimotoM,NakanlshiK.A2E,a lipofusctnfluorophore,inhunlanretinalpigmentedel>- ithelialcellsinculturelJ】.InvestOphthalmolV/sSc| 1999:40:2988..2995. 23BergmannM,SchfittF,Ho1zF,KopttzJ,InhibItlonofthe ATPrivenprotonpurePinRPElysosomesbythemajor lipofusctnfluorophoreA2一Emaycontributetothepatho- genesisofage-relatednlacnlardegenerationlJj,FASEBJ 2004;18(3):562-564, 24MartinL,Potentlalroleofretinalpigmentepithelial lipofusctnaccumulationinage-relatedmaculardegenera- tlonlJJ.ArehGerontolGertatrtcs2002;34(3):359-370. 25so1bachU,Kei11lauerC,KnabbenH,r01fS.Imaglngof retinalaut0l1uorescenceinpatientswitha鹰D.re1ated maculardegenemtionIJJ.RetJJ1a1997;17:385.389. 26Hr01zFG,Be11埘IanC,StaudtS,SchnttF,V61ckerHE.Fun. dusautonuorescenceanddeve1opmentof牙eographicat? mphyinage—re1atedmacu1ardegenemt1on【J].j_力vest 0phthI11VJsSc|2001;42:1051-1056. 葡萄肿,巩膜先天异常,巩膜肿瘤,巩膜变性等巩膜疾病的病 理,诊断及冶疗.全面体现了国内在巩膜疾病诊治这一 领域的水平.本书共分13章,全书约50万字,160余幅图 片,其中80余幅彩色图,图文并茂,便于读者对照,加深理解, 可直接指导,帮助诊断,实用性强,每章末均附有参考文献,可 供查阅.各地新华书店有售.