经肛门内镜手术：一个新技术

经肛门内镜手术：一个新技术 经肛门内镜手术:一个新技术 中国普外基础与『临床杂志2009年2月第16卷第2期 ChinJBasesClinGeneralSurg,Vo1.16,No.2,Feb.2009 18ChenYH,YaoWZ,GengB,eta1.Endogenoushydrogensul— fideinpatientswithCOPD[J].Chest,2005;128(5):3205 19伍蕊,姚婉贞,陈亚红,等.硫化氢在大鼠急性支气管哮喘 模型中的变化及意义[J].中华结核和呼吸杂志,2007;30 (7):522 20EtoK,OgasawaraM,UmemuraK,eta1.Hydrogensulfideis producedinresponsetoneuronalexcitation[J].JNeurosci, 2002;22(9):3386 21LeeSW,HuYS,HuLF,eta1.Hydrogensulphideregulates calciumhomeostasisinmicroglialcells[J].Gila,2006;54 (2):116 22Garcia-BereguiainMA,Samhan-AriasAK,Martin-RomeroFJ, eta1.Hydrogensulfideraisescytosoliccalciuminneurons throughactivationofL—typeCachannelsEJ].AntioxidRed— oxSignal,2008;10(1):31 23EtoK,AsadaT,ArimaK,eta1.Brainhydrogensulfideisse verelydecreasedinAlzheimer’sdisease[J].BiochemBiophys ResCommun,2002;293(5):1485 24ZhiL,AngAD,ZhangH,eta1.Hydrogensulfideinducesthe synthesisofproinflammatorycytokinesinhumanmonocytecell lineU937viatheERK—NF-kappaBpathway[J].JLeukocBiol, 2007;81(5):1322 25陈晓波,杜军保,耿彬,等.感染性和内毒素性休克大鼠动 脉组织中硫化氢的变化[J].基础医学与临床,2003;23(4): 384 26ZhangH,ZhiL,MooehhalaSM,eta1.Endogenoushydrogen sulfideregulatesleukocytetraffickingincecalligationandpunc— ture—inducedsepsisEJ].JLeukocBiol,2007;82(4):894 27ZhangH,HegdeA,NgSW,eta1.Hydrogensulfideup—regu— latessubstancePinpolymicrobialsepsis—associatedlunginjury EJ].JImmunol,2007;179(6):4153 28BhatiaM,WongFL,FuD,eta1.Roleofhydrogensulfidein acutepancreatitisandassociatedlunginjury[J].FASEBJ, 2005:l9(6):623 29TamizhselviR,MoorePK,BhatiaM.Hydrogensulfideactsas amediatorofinflammationinacutepancreatitis:invitrostudies usingisolatedmousepancreaticacinarcells[J].JCellMol Med,2007;11(2):315 30CollinM,AnuarFB,MurchO,eta1.Inhibitionofendogenous hydrogensulfideformationreducestheorganinjurycausedby endotoxemia[J].BrJPharmacol,2005;146(4):498 31BhatiaM,SidhapuriwalaJ,MoochhalaSM,etat.Hydrogen sulphideisamediatorofcarrageenan-inducedhindpawoedema intherat[J].BrJPharmacol,2005;145(2):14l 32戴鸿雁,凌亦凌,黄新莉,等.硫化氢在内毒素血症大鼠动脉 舒张反应性改变中的作用及其与一氧化氮的关系[J].河北医 科大学学报,2004;25(6):355 33DistruttiE,SediariL,MencarelliA,eta1.Evidencethathy— drogensulfideexertsantinOciceptiveeffectsinthegastrointesti— haltractbyactivatingKATPchannels[J].JPharmacoiExp Ther,2006;16(1):325 34LouLX,GengB,DuJB,eta1.Hydrogensulphide—inducedhy pothermiaattenuatesstress—relatedulcerationinratsIJ].Clin ExpPharmacolPhysiol,2008;35(2):223 35FiorucciS,SantucciL,DistruttiE.NSAIDs,coxibs,CIN0D andH2.~releasingNSAIDs:whatliesbeyondthehorizon[J_. DigLiverDis,2007;39(12):1043 36StrengT,AxelssonHE,HedlundP,eta1.Distributionand functionofthehydrogensulfidesensitiveTRPA1ionchannelin raturinarybladder[J].EurUrol,2008;53(2):391 (2008—06—2O收稿,2008—0828第二次修回) (本文编辑田超) 经肛门内镜手术:一个新技术 医海集萃 巴西saoPaulo大学运用一种新的经肛门内镜手术(transanalendoscopicoperation,TEO)对32 例直肠癌患者进行治疗. 观察并记录手术时间,住院时间,术后并发症,复发率等临床指标,与应用其他TEO(如 TEM,CTE等)的患者进行比较(数 据来源于不同作者的39篇文献报道).结果显示:该项新技术同样具有创伤小,并发症发生率 低,术后恢复快等优点,与其他 术式疗效相当,安全可行.由于运用了一种新的特制直肠镜,费用更低,易固定,无需进行直肠 充气,操作更简单,易于推广,尤 其适用于中下段直肠肿瘤[ActaCirBras,2008;23(Suppl1):93一lO4]. (四川大学华西医院肛肠外科万姗姗供稿) (供稿日期2008—10—16)