儿童EB病毒感染52例分析

儿童EB病毒感染52例 2008??9?o?%?:148?PE?ContemporaryMedicine,Spetember2008,IssueNo .148 ?L ?? ?% ?? 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[2]???c??.?%?S.????????.?:4??.?b??:???M???P?????v.2001?u83-84. [3]???????m??????.?<?????????P?????????]?????)?[?????????c??.?- ???M???%???x???m2003?m5?u2-3. ?n???????????n???????????o??X2 P ?c????(n=30)52530 ??????(n=30)2553026.67<0.01 ??2E??7???????????????????o???n EB?????<?????g?????????????????m???P???]?a?f???g?? ???m?c?n?y?????????????m?<?3???[???g???????u???%?????????m ???<?f???u?????????????????m?????<???????u?A?a???m?m?c?L ?????????L?????????n?u?h?[?m???????n?u?h?S?m?i?a??E2????[1] E0 ?:???4????EBV?P?????f???L???????m????????EBV?P???? ????E0 1E??L???;?? 1.1E????:?;???u?T???M??2005??2007????????????EBV- DNA?W?[??52?????f?L???;???o?1???[?BE2????E2?%??E2????E2 ?L???????????????????;???n?m???-?h34???m??18???m?h?u????E0 ????4??15???m????7???o?????4?8?R4??6??21???m6??8??11 ?f??EB?????P??52???4?? ?y????E??y???? [????]?????????f??EB?????P???r?L?????????????[???C???L??????E0????????2??52????????EBV-DNA?W?[???f?????? ?????????4??E0????EBV?P?????????R?u?h?SE0?????f??EBV?P?????<???????u?????m?L???????????u?h?SE0 [???=??]?f???NEBV?P???N?u?h?S ???m8??10??9???m10??15??12???m?????T?????4?8???y???O?m ???r?v???0?nE0 1.2E??L???????????u?[?u????????E2?????R?%?m???5?n????E2 ?????????[E2????????E0?n????50???m???e1??32?G?m????7.4 ?GE0???-????1???m?-??10???m????39???m???-?????R?%E0?n?? ????30??E0?L??12???m????1??E0????2???o1???????m1?????? ???nE0?????????[??24???o???-????18???m????1??E2????1??E2 ???e3????????1???nE0?????k?w50??E0?z?K?????[47???o5??? 14???m5????S?i1???m5???13???m5????S?i18???m5????S?i2???nE0 ????????????12???m???-??????8???m??????4??E0?n1?????? ?R?????????S?[?a???w??E0 3E????????????u?w?g??WB???g???m?a???? L???m?[????L3???m?4??N????5???mL???????m ???1?????u?????2?????0?????????%???f???o?y?????n ?????2?????0?-???%???f???o?y?????n 91 1.C174109 / 210109 /2227 411104411100 2008??9?o?%?:148?PE?ContemporaryMedicine,Spetember2008,IssueNo.148 ?L ?? ?% ?? C lin ic alM e d ic in e ???a???<???????:???????????????????m?????)?B?[?????[ ?u?????n???a???????0?g???????m?m???4????CT(highresolu- tionCT,HRCT)?]?v?R???a?????????????S???????n???????I ???m?<???????????????????N?[?????????m?????????)?B?[???? ???????????B???????n?????a??[1] E0?V???????)?B?[?????????p HRCT??150???????)?B?[?????????????????O ???eE????.?? [????]???????????a???????0?g???4????CT(HRCT?n?????]?????R?)?B?[???????????????g???????????????B?-?????OE0???? ??150???????gE2???????1??HRCT?????m?????]???4??????E0???????????????????a???????0?g?????R?D?????160?1???p???s?? ?140?1?m?m?w???????[?????g?u?????R?a?????????????H???m?7?1???????B?n?????a??(P<0.05?nE0?]?a?????]????E2???????????t?m ????????????????60?1?m?r?w???????[?????g(6.3?1?nE2???w????????(6.7%?n???)?B?????[???<?c?????????o7.1%?n???????B?n?v ???[?oP<0.05?nE083.3?1?<?c???????[?????g?????R?a???-??3.?M????3l?m?r?v?R?B?r?w???????[?????g???)?B?????[????E0?????? ?a???????0?gHRCT?????]?)?B?????[?????gE2?????????????B?-???n???????OE0 [???=??]?)?B?[?????????N?????g?N?????N???4???? [Abstract]ObjectiveThepurposeofthisstudywastoanalyzethepulmonarylobularstructureonHRCTofpulmonarytuberculosisandlungcancer withdiffusenodularandtoassessthediagnosticvalue.Methods150casesunderwenthighresolutionCT(HRCT)scansandtheimageswerereconstructed usinghigh-spatial-resolutionalgorithms.ResultsPulmonarylymphangiticcarcinomatosisexhibitedbeadedorirregularinterlobularseptawere60%and 40%,respectively,thereweresignificantdifferencebetweenwhichandhematogenousdisseminatedpulmonarytuberculosis(P<0.05).Intralobularlinear orfinereticularopacitiesinpulmonarylymphangiticcarcinomatosiswere60%,differentfromthehematogenousdisseminatedpulmonarytuberculosis andpulmonaryhematogenousmetastasesanddiffusenodularbronchioloalveolarcarcinoma(P<0.05).83.3%bronchogenicpulmonarytuberculosis showscentrilobularnodulesandbranchinglinearlesions(treeinbud),significantdifferencesbetweenwhichandthehematogenousdisseminated pulmonarytuberculosisorpulmonarymetastases.ConclusionTheHRCTsignsonthepulmonarylobularabnormalstructurehavetheimportantvalue indiagnosisandidentificationonpulmonarytuberculosisandlungcancer. [KeyWords]diffusenodularlungdiseases;pulmonarytuberculosis;lungcancer;HRCT ?x?m???????u?m?????<?????????r???B???????m?m?????R?????) ?B?????????????????g?<???-???i???????g??????E0?????m?:?? ?T??HRCT?;???????L???S???%???????????????)?B?[?????R?% ????????150?A?????m?????[?4????HRCT?????????m???????? ?????)?B?[??????????CT?????????B????E0 1E??;???r???? 1.1E????:?;???u?:???????)?B?[????150???m???R???%?? ???1?????u311100?????0?????R???????D???T?-???o???e?nE?E??????0 ???A?R?:?????M?%???o???.???n HB?a??110g/L17???o???R?????B?w?n?m?0???[??10?14??E0?w ?a?????g39???m?[??300??109 /L13??E0?f?g???0?g7???o7/45?m ??15.5%?nE0???????0?g1???o1/20?m??5%?nE0?w??8??100cm/ h?m?[??20cm/h26???o26/37?m??70.2%?nE0EBV-DNA???0?g ?????o??????28??,?w23??,?M?t??1???n?m?????0?g16??(16/ 41?m??39?1)E0???/???0?g1???o1/5?m??20?1?nE0 1.4E??????u?:???????r???????r?4?B???]?f?c?N??10mg/ kg.d?S???c?N??5mg/kg.d?m?G??????10mg/kg.d?????????? 2??17?G?m?????????o????,????????????7.3?GE0 2E????? EBV?P???<?f???g?????????????[?????m?V?????L???????u ?h?m???????[?????????m??????????E2??????E2?????????[E2?? ?v?[E2????E2??????E2????E2?S???w?0????????????????EBV- DNA?????W?[??E0?L???t?i?????a??E0?:???????%????????E2?? ??E2?????R?%?m?:?????????????n4??????EBV?P???m???????? ???R?)?[?z?K????E2?<?c??????E2????????E2?)?[?t???g???P?? ??????E0???O???????f???z?K?????[?S?S?iE2?????k?wE2?????? ???????[???g???m???5???n???????w??E2????E2????????E2?O?? ????E2???o???k?wE2?????W?[???M???????m???r?L?????????L?? ???????n?u?h?[?m?i?a??E2????E0???????????f?g???w??????E2?? ???B?wE2?w???????m???S???n?w?a??????E2?f?g???0?gE2?????? ?0?gE2?????0?gE2???/???0?gE2?M?t???0?g???M???????o?:???n ?w?a??????13??E2?f?g???0?g??15.5%?m???????0?g1???m20?1 ???/???0?g,39?1?????0?g?m77?1?w???0?g?m16?1?f?g???0?g?m1 ???M?t???0?g?nE0???r?:?????<???????u????E0?H???:???????? ???m?0?g???????????u??4???m???R?0???????p?<????EBV?P?? ???%???C?C?m???????5?0?????g?p???+??EBV?P??E0?????L???% ?o?????????????????????m?p???????????w???????m?????a??E0 ?????:?????p?x?[?m?M?????R?L???t??????E2????E2????E2 ?z?K?????[???????m???????????????p????????????EBV?P??E0 ?n????????PCREBV-DNA?????m?????????????????????m?? ???????a??E0 ???8???= []?????.???S???]?3???????:???b???u???M???P?????v?m 3535 92 1...2.1998: 2-7.