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World Chin J Digestol 2005 March 1:13(5):617—620
世界华人消化杂志 ISSN 1009—3079 CN 14—1260/R
2 00 5年版权归世界胃肠病学杂志社
·基础研究BASIC RESEARCH·
生长抑素诱导猕猴外周血中性粒细胞凋亡
许兰涛,唐承薇
许兰涛,唐承薇,四川大学华西医院消化内科 四川省成都市 610041
许兰涛.男,1 964—07—03生.副主任医师,副教授,博士.主要从事消化内科
的研究.
国家自然科学基金资助项目.No.30170875
项且负责人:唐承薇.61 0041.四川省成都市,四川大学华西医院消化内科
sccdlx@sohu.com
电话:028—85445341
收稿日期:2004—1 2—22 接受日期:2005—01—20
Effect of som stostatin on apoptosis
of polymorphonuclear neutroph¨ s of
rhesus monkey
Lan-Tao Xu,Cheng-Wei Tang
Lan-Tao Xu,Cheng-Wei Tanq,Department of Digestology.West China
Hospital,Sichuan University,Chengdu 610 1,Sichuan Province,China
Supported by Nafional Science Foundadon of China,No.30170875
Correspondence to:Cheng—Wlei Tang.Department of Digestology,W st
China Hospital,Sichuan University,Chengdu 61Oo4l,Sichuan Province,
China.sccdlx@sohu.com
Received:2OO4.12.22 Accepted:2005.01.20
Xu LT,Tang CW .Effect of somstostatin on apoptosis of polymor—
phonuclear neutrophils of rhesus monkey.Shiiie Huaren Xiaohua
Zazhi 2OO5j13(5):617—620
摘要
目的:观察生长抑素对猕猴外周血中性粒细胞的作用
:用生长抑素与猕猴外周血中性粒细胞共同孵育一定
时间后,采用流式细胞仪、DNA电泳、电镜观察猕猴外
周血中性粒细胞的形态变化,细胞DNA含量分布变化.
结果:生长抑素能诱导猕猴外周血中性粒细胞凋亡,
在形态学上
现为细胞膜起泡、染色质固缩、核碎裂、
凋亡小体形成;电泳呈凋亡特征性Ladder带;流式细胞仪
分析显示,PMN凋亡比例增r~(22.1%vs50.5%.P
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ISSN 1009-3079 CN 14—1260/R 2005年版权归世界胃肠病学杂志社
世界华人消化杂志2665牟由月刊改为半月刊
编辑 潘伯荣 审读 张海宁
· 消息·
本刊讯 中国科技期刊引证报告(2003年版):2002年度世界华人消化杂志总被引频次4151,影响因子1.926,即年指标0.424,
他引总引比0.45,引用于U数1 73,扩散因子4.2,被引半衰期2.99,地区分布数26,机构数1 38,国际
比0.03,基金
论文比0.27.2002年度各学科影响因子较高的3种期刊排名:世界华人消化杂志影响因子1.926,临床医学排名第2位.2002年
度总被引频次较高的20种期干U排名:世界华人消化杂志总被引频次4151,排名第1位.世界华人消化杂志被评为中国科技核心期
干IJ,《中文核心期刊要鼠总览》20o4年版内科学类的核心期刊,中国科技论文统计源期刊,2001年度第一届中国百种杰出学术期
刊,2003年度中国百种杰出学术期刊.世界华人消化杂志的英文摘要被美国 《化学文摘》,荷兰 《医学文摘库/医学文摘》,俄罗
斯 《文摘杂志》收录.为适应我国消化病学专业基础与临床研究的快速发展,从2005年开始,世界华人消化杂志将由月刊改为半
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