保留盆腔自主神经对老年男性直肠癌TME术后性功能和泌尿功能的影响

phism and the risk of stroke:a case-control study in an Indian population [J]. Brain Res Bull,2008 ;75( I ):158-65. @@6. Bevan S, Porteous L, Sitzer M. Phosphodiesterase 4D gene, ischemic stroke, and asymptomatic carotid atherosclerosis [ J ]. Stroke, 2005 ; 36 (5) :949-53. @@7. Brophy VH, Ro SK, Rhees BK,et al. Association of phosphodiesterase 4D polymorphisms with ischemic stroke in a US population stratified by hy pertension status[ J]. Stroke,2006 ;37 ( 16 ) : 1385-90. @@8. Woo D, Kaushal R, Kissela B,et al. Association of phosphodiesterase 4D with ischemic stroke. A population-based cass-control study[ J]. Stroke, 2006;37(2) :371-6. @@9. Nakayama T, Asai S, Sato N, et al. Genotype and haplotype association study of the STRK1 region on 5q12 among Japanese:a Case-Control study [J]. Stroke,2006 ;37( 1 ) :69-76. @@10. Zee RY, Brophy VH, Cheng S. Polymorphisms of the phosphodiesterase 4D, cAMP-Specific ( PDE4D ) gene and risk of ischemic stroke: a prospec tive,nested case-control evaluation[J]. Stroke,2006;37(8) :2012-7. @@11. Lohmussaar E, Gschwendtner A, Mueller JC,et al. ALOX5AP gene and the PDE4D gene in a central European population of stroke patients [J]. Stroke,2005;36(4) :731-6. @@12. Newcombe PJ,Verzilli C,Casas JP,et al. Multilocus Bayesian meta-anal ysis of gene-disease associations [ J ]. Am J Hum Genet, 2009 ; 84 ( 5 ) : 567 -80. 2011-11-05 2012-03-10 保留盆腔自主神经对老年男性直肠癌TME术后性功能和泌尿功能的影响 张 军 丁海涛 韩智君 新疆医科大学第六附属医院普外科，新疆 乌鲁木齐830002 [摘要] 目的 探讨保留盆腔自主神经(PANP)的直肠全系膜切除术(TME)对老年男性直肠癌患者性功能和泌尿功能的影响。方法 将36 例直肠癌患者随机分为观察组和对照组：观察组行TME+ PANP治疗，对照组行常规TME治疗。术后进行半年随访，评价患者性功能和泌尿功能，随 访3年观察患者局部复发情况。结果 观察组泌尿功能障碍、性功能障碍发生率较观察组低(P＜0.05)，术后3年两组患者的局部复发率分别为 11.1％和16.7％，生存率为74. 2％和71.4％，两组间的差异并无统计学意义(P＞0.05)。结论 保留盆腔自主神经的直肠癌根治术可以较好地保护 老年男性患者的性功能和泌尿功能，而患者局部复发率并没有升高。 直肠癌；全系膜切除术；盆腔自主神经；泌尿功能障碍；性功能障碍 R735 A 1005-9202( 2012 ) 12.2512-02 10. 3969/.j.issn. 1005-9202.2012. 12.031 张军(1960-),男，副主任医师，主要从事胃肠外科疾病的 诊治工作。 万方数据 @@1. Phang PT. Total mesorectal excision:technical aspects [ J]. Can J Surg, 2004;47(2) :130-7. @@2. Maurer CA. Urinary and sexaal function after total mesorectal excision [ J ]. Recent Results Cancer Res,2005 ; 165 : 196-204. @@3.顾晋.直肠肛门部恶性肿瘤[M].北京：北京大学医学出版社， 2007:113. @@4. Rosen RC,Riley A,Wagner G,et al. The international index of erectile function(IIEF) :a multidimensional scale for assessment of erectile Dys function[ J]. Urology, 1997 ;49 (6) :822 -30. @@5.惠希增，宋世德，郑海燕，等男性直肠癌直肠系膜切除术中保留盆 腔自主神经对排尿及性功能影响的研究[J].中华泌尿外科杂志， 2010；31 (7)：489-92. @@6.荫华，张寰，高嵩，等.盆腔自主神经保留对直肠前切除术后 排尿及性功能影响的观察[J].中华普通外科杂志，2003；189(4): 222-4. @@7. Maas CP,Moriya Y,Steup WH,et al. Radical and nerve-preserving sur gery for rectal cancer in The Netherlands:a prospective study on morbidi ty and function outcome [ J ]. Br J Surg, 1998 ; 85 ( 1 ) :92 -7. @@8. Kneist W,Junginger T. Validity of pelvic autonomic nerve stimulation with intraoperative monitoring of bladder function following total messorectal ex cision for rectal cancer[J]. Dis Colon Rectum,2005 ;48(2) :262-9. @@9. Ameda K,Kakizaki H,Koylanagi T,et al. The long-term voiding function and sexual function after pelvic nerve-sparing radical surgery for cancer [J]. Int J Urol,2005;12(3) :256-63. @@10. Lee DK,Jo MK,Song K,et al. Voiding and sexual function after auto nomic-nerve-preserving surgery for rectal cancer in disease-free male pa tients[ J]. Korean J Urol,2010;51 (12) :858-62. 2011-09-09 2012-02-29 万方数据 保留盆腔自主神经对老年男性直肠癌TME术后性功能和泌尿功 能的影响 作者： 张军， 丁海涛， 韩智君 作者单位： 新疆医科大学第六附属医院普外科,新疆 乌鲁木齐,830002 刊名： 中国老年学杂志 英文刊名： Chinese Journal of Gerontology 年，卷(期)： 2012,32(12) 参考文献(10条) 1.Ameda K;Kakizaki H;Koylanagi T The long-term voiding function and sexual function after pelvic nerve-sparing radical surgery for cancer 2005(03) 2.Kneist W;Junginger T Validity of pelvic autonomic nerve stimulation with intraoperative monitoring of bladder function following total mesorectal excision for rectal cancer 2005(02) 3.Maas CP;Moriya Y;Steup WH Radical and nerve-preserving surgery for rectal cancer in The Netherlands:a prospective study on morbidity and function outcome 1998(01) 4.荫华;张寰;高嵩 盆腔自主神经保留对直肠前切除术后排尿及性功能影响的观察 2003(04) 5.惠希增;宋世德;郑海燕 男性直肠癌直肠系膜切除术中保留盆腔自主神经对排尿及性功能影响的研究 2010(07) 6.Rosen RC;Riley A;Wagner G The international index of erectile function(IIEF):a multidimensional scale for assessment of erectile Dysfunction 1997(06) 7.顾晋 直肠肛门部恶性肿瘤 2007 8.Maurer CA Urinary and sexual function after total mesorectal excision 2005 9.Lee DK;Jo MK;Song K Voiding and sexual function after autonomic-nerve-preserving surgery for rectal cancer in disease-free male patients 2010(12) 10.Phang PT Total mesorectal excision:technical aspects 2004(02) 本文链接：http://d.g.wanfangdata.com.cn/Periodical_zglnxzz201212031.aspx