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免疫副作用及其siRNA序列设计与化学修饰

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免疫副作用及其siRNA序列设计与化学修饰 !" !"##$%&’()*+, $%!"#-./012345 & !"# !"##$ % !"##$ & !"##’() !$%"&& !"#!"#$%$&’(%)*’(+,-./0 12 $%&&"$3 $’456$78#$’($-./9 :; $(&&$)’ 67 *+,-. ,-.?@78ABCDEFGH-.IJKLM+,>NOPQ/0RSTU0 *+,-.VWXYZ[\] ^_‘a’(bc9 d=?@efghFi>jk9 lm]nopqrstunvEF>wx9 N]Hy#zs ,-.?@ 78>{O/|}~o...
免疫副作用及其siRNA序列设计与化学修饰
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! 万方数据 干扰RNA的非靶免疫副作用及其siRNA序列与化学修饰 作者: 韩秋菊, 张彩, 张建, 田志刚, HAN Qiu-Ju, ZHANG Cai, ZHANG Jian, TIAN Zhi-Gang 作者单位: 韩秋菊,张彩,张建,HAN Qiu-Ju,ZHANG Cai,ZHANG Jian(山东大学药学院免疫药理与免疫治疗研究所,济南 ,250012), 田志刚,TIAN Zhi-Gang(山东大学药学院免疫药理与免疫治疗研究所,济南,250012;中国科学技术 大学免疫学研究所,合肥,230027) 刊名: 生物化学与生物物理进展 英文刊名: PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 年,卷(期): 2007,34(4) 被引用次数: 2次 参考文献(30条) 1.Hornung V;Guenthner M;Bourquin C Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7 2005(03) 2.Sledz C A;Holko M;Veer M J Activation of the interferon system by short-interfering RNAs[外文期刊] 2003(09) 3.Pai SI;Lin Y Y;Macaes B Prospects of RNA interference therapy for cancer[外文期刊] 2006(06) 4.Barik S;Bitko V Prospects of RNA interference therapy in respiratory viral diseases:update 2006 2006(11) 5.Sontheimer E J;Carthew R W Silence from within:Endogenous siRNAs and miRNAs[外文期刊] 2005(1) 6.Elmen J;Thonberg H;Ljungberg K Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality [外文期刊] 2005(01) 7.Puthenveetil S;Whitby L;Ren J Controlling activation of the RNA-dependent protein kinase by siRNAs using site- specific chemical modification[外文期刊] 2006(17) 8.Marques J;Williams B Activation of the mammalian immune system by siRNAs[外文期刊] 2005(11) 9.Morrissey D V;Lockridge J A;Shaw L Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs[外文 期刊] 2005(08) 10.Scacheri P C;Rosen O R;Caplen N J Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells[外文期刊] 2004(07) 11.Jackson A L;Bartz S R;Schelter J Expression profiling reveals off-target gene regulation by RNAi[外文期刊] 2003(06) 12.Judge A D;Sood V;Shaw J R Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA [外文期刊] 2005(04) 13.Soutschek J;Alinc A;Bramlage B Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs[外文期刊] 2004(11) 14.Naito Y;Yamada T;Matsumiya T dsCheck:highly sensitive off-target search software for double-stranded RNA-mediated RNA interference 2005 15.Marques J T;Devosse T;Williams B A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells[外文期刊] 2006(05) 16.Sioud M Single-stranded small interfering RNA are more immunostimulatory than their double-stranded counterparts:A central role for 2'-hydroxyl uridines in immune responses[外文期刊] 2006(5) 17.Heil F;Hemmi H;Bauer S Species-specific recognition of single-stranded RNA via Toll-like receptor7 and 8[外文期刊] 2004(5676) 18.Alexopoulou L;Holt A;Medzhitov R Recognition of double-stranded RNA and activation of NF-kappa B by Toll-like receptor 3 2001(6857) 19.Fedorov Y;Anderson E M;Birmingham A A Off-target effects by siRNA can induce toxic phenotype 2006(07) 20.Lin X;Ruan X;Anderson M G siRNA-mediated off-target gene silencing triggered by a 7 nt complementation[外文期刊] 2005(14) 21.Sioud M Innate sensing of self and non-self RNAs by Toll-like receptors[外文期刊] 2006(04) 22.Mello C C;Conte D J Revealing the world of RNA interference[外文期刊] 2004(7006) 23.Judge A D;Bola G;Lee A H Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo[外文期刊] 2006(03) 24.Dowler T;Bergeron D;Tedeschi A L Improvements in siRNA properties mediated by 2'-deoxy-2'-fluoro-β-D-arabinonucleic acid (FANA) 2006(06) 25.Song E;Zhu P;Lee S K Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors[外文期 刊] 2005(06) 26.Kalavrizioti D;Vourekas A;Stamatopoulou V RNA-mediated therapeutics:from gene inactivation to clinical application [外文期刊] 2006(16) 27.Jiang W;Sun R;Wei H Tol-like receptor 3 ligand attenuates LPS-induced liver injury by down-regulation of toll-like receptor 4expression on macrophages[外文期刊] 2005(47) 28.Dong Z;Wei H;Tian Z Involvement of natural killer cells in PolyI:C-induced liver injury[外文期刊] 2004(06) 29.Kariko K;Bhuyan P;Capodici J Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through Toll-like receptor 3[外文期刊] 2004(11) 30.Zhou R;Wei H;Sun R Recognition of double-stranded RNA by Toll-like receptor 3 induces severe small intestinal injury in mice 2007(07) 引证文献(2条) 1.柳觐.相微微.张怀刚 RNA干扰技术在小麦中的应用研究进展[期刊论文]-麦类作物学报 2009(4) 2.张彩.田志刚 天然免疫识别机制及天然免疫受体的相互调节[期刊论文]-生物化学与生物物理进展 2008(2) 本文链接:http://d.g.wanfangdata.com.cn/Periodical_swhx200704002.aspx
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