咖啡酸苯乙酯
Phenethyl caffeate
--New material of Bio-engineering, the renewable histiocyte catalyst Cell is the basic unit of the life activities. Under the common physiological conditions, cells and tissues continuous turn old and apoptosis, the newborn cells and tissues are continuously add, in that way they can keep the original structure and function and maintain the integrity of the tissues , organs and stability; but under Pathologic state, cells and tissues necrosis or defect, the damaged cells can use their own regeneration to make the same cell proliferation, differentiation and restore original structure and function, but cells in the natural conditions , theirs self regeneration and repair will take a long time and process.
Through a large number of experimental, Scientists had studied a spice -- Phenethyl caffeate, it is a magical promote cell and have the function of regenerate fast. The scientists take an experiment on a dog neck, and cut off a little part of skin on the A, B, C, three parts, making a 2 cm trauma in diameter. With Phenethyl caffeate ethanol solution on part A, with ethanol in part B and don't do anything in part C. The second day, A part display a treatment effect: the bottom dry, trauma area has shrunk and over the next few days, the wound continue to shrink, in the sixth day, the wounds healed completely. The one only with alcohol is healing slowly. When part A is healing, the other two parts still have one more than 1 cm diameter wound. The experiments proved that Phenethyl caffeate has the function to make cells organization regenerate. The birth of the study has caused a stir in the medical profession. In the medical world also caused a high degree of attention and widespread application. For example, it can short the wound healing time after have a damaged skin tissues surgery; in the body it can speed up the cure of gastric ulcer; it can accelerate the repairing liver cells of liver disease.
【Name】Phenethyl caffeate
【Molecular】CHO17164
【Content】98%
【CAS No.】104594-70-9
【Melt Point】185.1 ?
【Appearance】Yellow to light yellow crystalline solid
【Solubility】Insoluble in water and alcohol
【Usage】
Phenethyl caffeate not only has function of promote the cells regeneration rapidly, but also has the effect of anti-inflammatory and antitumor. Being as the important raw materials and intermediates, Phenethyl caffeate can be widely applied in the medical field. The structure of Phenethyl caffeate contains catecholamine structure; it is a kind of strong antioxidant. The experiment showed that Phenethyl caffeate can reduce NOS of
consumption through scavenging activities oxidation material and inhibit xanthine (X0), , and then have the effect of antioxidant.
Phenethyl caffeate can inhibit the harpoons food glue the induction of arthritis, pleurisy adjuvant and rat enough swelling; Have a good effect at their sexual immune diseases such as rheumatoid arthritis, ulcerative colitis and systemic lupus erythematosus (sle) anti-inflammatory. Phenethyl caffeate still can restrain prostaglandin (PG) and BaiSanXi synthesis of prostitutes has certain curative effect.
【Authoritative research and customer application】
Phenethyl caffeate has anti-cancer activity, can inhibit tumor cell proliferation, of cancer cells have certain poison effect, and cancer cell has a specific damage. University of overseas Chinese, Jinan university organization transplantation and immune experiment center, south China university, third military medical university hospital DaPing field surgical research institute cancer center, Zhengzhou university biological engineering, Lanzhou university in dozens of authoritative research institutions to coffee expert acid ethyl benzene in colorectal cancer, vascular smooth muscle cell proliferation, metastatic cancer, colon cancer, and the glioma, pulmonary fibrosis, cervical cancer the effect, found the Phenethyl caffeate mechanism is involved in the induction of natural cell death, At the same time for malignant lesions organizations have cell toxic effect, Phenethyl caffeate in very trace concentration can improve the tumor factors (12-0-14 by acylation alcohol-13-wave acetate) cause inflammation, and demonstrated that can effectively restrain the foreign carcinogenic substance; Phenethyl caffeate to a 60, Bel HL a 7402 and He1a tumor cells have better inhibition activity, inhibition rate reached 56.05%, 48.78% and 56.05% respectively. Phenethyl caffeate to HL-60 cells IC50 concentration was 1.0 u M, 5.0 u M and 1. 5 μ M when can inhibit respectively DNA, RNA and protein synthesis. The
study also showed that Phenethyl caffeate has a good work of melanoma, colon cancer
and stomach cancer cell lines role of very intense, show the characteristics of restrain
cancer cell