医学臭氧大自血疗法

医学臭氧大自血疗法 奉节县医学会医药卫生科技项目评价 申报表 项目名称 现代康复技术 肢体功能锻练 申报单位: 奉节县中医院 申报科室: 康复科 项 目 人: 来明 联系电话: 日期: 2012-11-23 卫生局编号: 奉节县卫生局监制 2009年制 奉节县医学会医药卫生科技项目评价申报表 application; infection and antibacterial drug of clinical application; transfusion refers to levy; nutrition support of adapted card and clinical application; common life support technology (as cycle breathing support, and nutrition support,) and emergency technology of application; common guardianship instrument using. Look: shock, cardiac respiratory arrest and acute organ failure, systemic inflammatory response syndrome and severe infection and multiple organ dysfunction syndrome (MODS), severe disturbance of body fluid environment such as critical theory and progress of the illness. 2. basic requirements (1) species and cases of study requirements: severe pneumonia in disease-disease myocardial infarction ... 3. high requirements (1) learning disease species: disease species disease species image radiation: rheumatic heart congenital heart intestinal Crohn's (Crohn) disease intestinal tuberculosis bile duct cancer chronic pancreatic inflammatory urinary system stone urinary system tumor adrenal disease thyroid disease cranial within infection nervous system tumor nuclear medical: Digest road bleeding explicit like brain blood flow perfusion explicit like testicular blood pool explicit like salivary glands explicit like (2) clinical knowledge, and skills requirements: understand various image check 填报单位:奉节县中医院 填报人及电话 来明 56529171 2010年 12月 23日 项 目 初评 臭氧大自血疗法 奉节中医院技术委员会 名 称 单位 评 价 新( )新技术(?)新材料()引进创新( )新产品( )其它( ) 性 质 初 评 等 级 来明、罗莹、毛荣完成单位 主要完成 兰、邓阳春、寇家奉节县中医院 康复科 及科室 人员 繁、袁兴、 余友池、 胡静 项目简介 医用臭氧治疗自体血回输、肌内注射。 1.可增强血液流动性，改善局部组织供氧; 2.过氧化氢和医用臭氧可恢复细胞功能，增强细胞的氧代谢功能。 “红细胞缗钱样堆积”是动脉栓塞形成的主要表现，它的形成和红细胞表面极性变化有关系，应用医用臭氧治疗后，患者红细胞的流变性增加，提高了红细胞通过毛细血管的能力，增加了心脏以及其他重要组织的氧气供应。 成效及影响 . 臭氧医学发源于十九世记末叶,那时人群已已经采用固陋的臭氧发生设施举行医用臭氧的制备,开展奋战创伤的治疗,好比外科传染,战壕足等的治疗,治疗方式重要引用利用临时制备的臭化合水开展清创,其效用主导是广谱杀菌、抗炎、促成局部组织再生等机理,因为成效良好,从而极大唤起了人群对臭氧医学爱好; 。在臭氧医学发展的过程中,因为臭氧自身享有: 1、 强氧化作用 2、 促成血液轮回作用 3、 促成含氧血红蛋黄向号召释放氧气从而增高氧代谢水平 4、 免疫惊险及持平作用 5、 广谱抗菌效用 6、 清除自由基效用 7、 清除肿瘤细胞 目前臭氧医学已在世面范围内已要到了极大的发展,可证实资料国外网站:the International Medical Ozone Society(国际医学臭氧协会)或者Ozone Therapy(臭氧治疗)或者Ozone Therapy Center(臭氧治疗中心)。 application; infection and antibacterial drug of clinical application; transfusion refers to levy; nutrition support of adapted card and clinical application; common life support technology (as cycle breathing support, and nutrition support,) and emergency technology of application; common guardianship instrument using. Look: shock, cardiac respiratory arrest and acute organ failure, systemic inflammatory response syndrome and severe infection and multiple organ dysfunction syndrome (MODS), severe disturbance of body fluid environment such as critical theory and progress of the illness. 2. basic requirements (1) species and cases of study requirements: severe pneumonia in disease-disease myocardial infarction ... 3. high requirements (1) learning disease species: disease species disease species image radiation: rheumatic heart congenital heart intestinal Crohn's (Crohn) disease intestinal tuberculosis bile duct cancer chronic pancreatic inflammatory urinary system stone urinary system tumor adrenal disease thyroid disease cranial within infection nervous system tumor nuclear medical: Digest road bleeding explicit like brain blood flow perfusion explicit like testicular blood pool explicit like salivary glands explicit like (2) clinical knowledge, and skills requirements: understand various image check 主持 评价 主持签字: 单位 年 月 日 意见 组织 评价 单位主管领导签字: 意见 年 月 日 注:(1)版面不够可另附页，并要同时附项目完成情况报告及初评资料。 (2)表列评价性质栏括号内划“?”表示。 项目实施报告 一、技术理论 1、增强粒细胞的吞噬功能，增加粒细胞的数量，增加机体抗感染能力。 2、刺激单核细胞的形成，清除、扑获及杀死细菌。 3、激活T细胞、NK细胞等免疫活性细胞，促进细胞因子(如干扰素、白介素)释放。医用臭氧浓度为50mg/L，血清中干扰素数量最大值。 4、增强中性粒细胞产生超氧阴离子、过氧化氢、氢氧自由基的能力、促进中性粒细胞爆发的过程，增强机体杀菌能力。 5、医用臭氧和免疫细胞表面不饱和脂肪酸反应生成脂质过氧化氢链，脂质过氧化氢链进入细胞内，可以激活核因子NFKB，从而激活细胞mRNA的复制、转录和翻译，促进蛋白合成、细胞质因子释放。 6、医用臭氧与体液反应产生过氧化氢，过氧化氢可穿透细菌和病毒微的蛋白质膜，破坏膜保护，使细菌和病毒的脂质膜和蛋白质膜融合，导致细胞膜变硬易碎。 7、过氧化氢可通过它的强氧化作用破坏细菌及病毒的细胞膜，杀灭细菌和病毒。 8、过氧化氢可穿透细菌和病毒的蛋白质膜，打开细菌和病毒的细胞核，使DNA暴露，破坏其DNA。 9、医用臭氧直接破坏RNA和DNA而灭活病毒。 10、活化红细胞，提高三磷酸腺苷(ATP)二磷酸甘油(DGP)水平，增强血液的携氧量，促application; infection and antibacterial drug of clinical application; transfusion refers to levy; nutrition support of adapted card and clinical application; common life support technology (as cycle breathing support, and nutrition support,) and emergency technology of application; common guardianship instrument using. Look: shock, cardiac respiratory arrest and acute organ failure, systemic inflammatory response syndrome and severe infection and multiple organ dysfunction syndrome (MODS), severe disturbance of body fluid environment such as critical theory and progress of the illness. 2. basic requirements (1) species and cases of study requirements: severe pneumonia in disease-disease myocardial infarction ... 3. high requirements (1) learning disease species: disease species disease species image radiation: rheumatic heart congenital heart intestinal Crohn's (Crohn) disease intestinal tuberculosis bile duct cancer chronic pancreatic inflammatory urinary system stone urinary system tumor adrenal disease thyroid disease cranial within infection nervous system tumor nuclear medical: Digest road bleeding explicit like brain blood flow perfusion explicit like testicular blood pool explicit like salivary glands explicit like (2) clinical knowledge, and skills requirements: understand various image check 进血红蛋白的分裂，降低氧与血红蛋白亲和力，提高氧从血液向细胞的扩散。 11、在肿瘤部位提供足量的氧，选择性抑制肿瘤生长;杀灭抑制致癌病毒;激活免疫系统，增加肿瘤坏死因子，促使机体抵抗感染和肿瘤。 12、强氧化性，氧化降解石化物。 13、提高血氧饱和度，改善血液循环，激活细胞代谢，提高人体的组织活性，从而组织的供氧状况得到改善;医用臭氧能改变血液的结构以及动脉、静脉中的流动方式;增加红细胞的弹性，提高血液通过毛细血管的能力，加速氧代谢。 14、降低血小板的诱导聚集(凝血酶 胶原蛋白)，使血栓解体。 15、氧化粘附在血管壁上的色斑等脂肪物质，增加血管弹性。 16、促进三羧酸循环，促进对糖的利用，增加能量释放，刺激基本代谢，激活人体正常代谢。 二、技术特征 大自血操作步骤 1.取血 [1] 利用输血器械从手臂静脉血管中抽取100毫升血液至一次性真空无菌反应血袋中。抽取的血液与血袋中的抗凝剂相混合，防止血液凝结。 2.混合臭氧 然后通过一根注射器抽取100ml的臭氧掺入血液中。血液与臭氧的比例为1:1，臭氧浓度为47微克/ml，以缓慢的圆周运动将血液-臭氧混合物振动大约1分钟:血液由此变为鲜红色的含氧血。 3.回输血液 通过静脉注射将血液重新输回血管(100滴/分钟左右)，年老者及心功能不全者宜调慢滴速(50滴/分钟左右)。臭氧疗法医生协会建议在静脉注射时使用生理盐水溶液等。臭氧剂量的选择由所治疗的疾病类型决定。 项目实施报告 application; infection and antibacterial drug of clinical application; transfusion refers to levy; nutrition support of adapted card and clinical application; common life support technology (as cycle breathing support, and nutrition support,) and emergency technology of application; common guardianship instrument using. Look: shock, cardiac respiratory arrest and acute organ failure, systemic inflammatory response syndrome and severe infection and multiple organ dysfunction syndrome (MODS), severe disturbance of body fluid environment such as critical theory and progress of the illness. 2. basic requirements (1) species and cases of study requirements: severe pneumonia in disease-disease myocardial infarction ... 3. high requirements (1) learning disease species: disease species disease species image radiation: rheumatic heart congenital heart intestinal Crohn's (Crohn) disease intestinal tuberculosis bile duct cancer chronic pancreatic inflammatory urinary system stone urinary system tumor adrenal disease thyroid disease cranial within infection nervous system tumor nuclear medical: Digest road bleeding explicit like brain blood flow perfusion explicit like testicular blood pool explicit like salivary glands explicit like (2) clinical knowledge, and skills requirements: understand various image check 三、总体性能指标 1(本项目在所属领域的状况: 全国臭氧医学的引进始于2000年,首先军医高校的何晓峰教授初次将臭氧椎间盘髓核融解术引进我国的医学界, 在这而后,臭氧医学逐步从单一治疗椎间盘凸起症发展到治疗骨科、心脏内科、变态内科、烫伤科、糖尿病内分泌科、肿瘤科、病痛科等临床科室的各样病症;臭氧治疗获得了日益增长的全世界的瞩目。臭氧医学现在已经拥有了关于在一些疾病中，理解和推荐臭氧治疗作为首选或是联合传统治疗的总体知识框架。现在，臭氧已经可以被通过生物化学水平和临床水平进行验证。到目前为止，最先进、可靠的应用方法还是臭氧大自体血疗法 2(主要研究内容 一、臭氧自体血回输疗法和疗程 1、心脑血管疾病治疗:迅速改善中风、冠心病、心绞痛症状，在最短的时间内从根本上修复病变组织。应用臭氧治疗后，患者红细胞的流变性增加，提高了红细胞通过毛细血管的能力，增加了心脑的氧气供应。臭氧和过氧化氢可以加速三羟酸循环，增加基础代谢，促进碳水化合物和脂肪的代谢，分解黏附在血管壁上的脂肪。自由基团的过度产生是导致心脏病的重要因素，臭氧可以激活谷胱甘肽酶过氧化氢酶和超氧化物歧化酶，有助于自由基团的清除。这些对于降低高血脂、血液黏稠度，都有明显的作用。 2、糖尿病治疗:臭氧治疗对于恢复胰岛功能效果良好，降糖效果明显，病人可以减量或停用降血糖药品。 3、病毒性肝炎治疗:对乙肝、丙肝有较好治疗效果，无副作用，成本低。根据国内文献报道对于丙肝转阴和乙肝大三阳转小三阳疗效明显。 4、烧烫伤治疗:采用体袋充臭氧气体和臭氧水疗法，烧烫伤患者感染率为零，愈合速度远好于传统理疗和药物疗法。 5、腰间盘脱出微创治疗:臭氧可以降解局部脱出髓核组织，达到治疗目的。 6、其他方向亚健康人群:臭氧治疗有良好的降血脂及改善器官供血功能，溃疡性结肠炎、宫颈糜烂、荨麻疹、免疫系统疾病等。 二、在临床方面的应用: 1、感染性疾病(细菌、病毒、真菌、感冒)、脓肿、肛裂、褥疮、瘘、真菌性疾病、疔疮、齿龈炎、绵延难治的骨髓炎、腹膜炎、鼻窦炎、胃炎和外阴炎、对抗生素类耐药的细菌或厌氧菌。 治疗方法:轻度用臭氧水局部冲洗，中重度配合每隔一天的自血疗法。 2、慢性肝炎、脂肪肝、肝硬化、药物性肝炎。 治疗方法:通过自血疗法，每隔一天一次，—疗程大约。 3(技术特点、创新及成果 1、弧菌、病菌、真菌等灭活效用。 臭氧透过氧化弧菌细胞膜上的磷脂和脂蛋黄来毁坏细胞膜的完整性。对于真菌,臭氧能够按捺真菌在某一阶段的发育。对于病菌,臭氧可以败坏毒剂衣壳,而且经过过application; infection and antibacterial drug of clinical application; transfusion refers to levy; nutrition support of adapted card and clinical application; common life support technology (as cycle breathing support, and nutrition support,) and emergency technology of application; common guardianship instrument using. Look: shock, cardiac respiratory arrest and acute organ failure, systemic inflammatory response syndrome and severe infection and multiple organ dysfunction syndrome (MODS), severe disturbance of body fluid environment such as critical theory and progress of the illness. 2. basic requirements (1) species and cases of study requirements: severe pneumonia in disease-disease myocardial infarction ... 3. high requirements (1) learning disease species: disease species disease species image radiation: rheumatic heart congenital heart intestinal Crohn's (Crohn) disease intestinal tuberculosis bile duct cancer chronic pancreatic inflammatory urinary system stone urinary system tumor adrenal disease thyroid disease cranial within infection nervous system tumor nuclear medical: Digest road bleeding explicit like brain blood flow perfusion explicit like testicular blood pool explicit like salivary glands explicit like (2) clinical knowledge, and skills requirements: understand various image check 氧化作用来毒剂经过病菌和弧菌连系,既而败坏病菌的重建轮回。薄弱的细胞膜上的酶衣对于毒剂的入侵是易损的,同时对于身上里面的氧化和清除作用也是敏感的,进一步机体用健康的细胞顶替本来病变细胞; 2、增强血液轮回 在轮回性疾病中,红细胞凝结妨碍血流透过小的毛细血管,由于红细胞总的表层积递减,下降氧的吸取,既而下降号召携氧量;臭氧可以减低或者化除红细胞的凝聚,同时光复红细胞的适应性,进一步提升血液携氧财力。动脉分压增高和血液粘滞性降低使团体充氧作用增高;臭氧也足以氧化动脉内壁上的斑块,使代谢产物要到清除,血管壁更畅快;臭氧足以改善橘红细胞的舒展性,提升穿越毛细血管能力,利于向号召供氧 3、增强氧代谢 臭氧使橘红细胞内糖酵解率升高,致使二磷酸甘油(2,3-DPG)增多,2,3-DPG能够引致红细胞对组织释放氧能力的递加;臭氧同时得以使作为自由基清除剂的酶的发生的增长,包含谷胱甘肽过氧化物酶、过氧化氢酶、超化合物歧化酶。臭氧经过丙酮酸酯氧化羧化效用,加速机体的三羧酸轮回,惊险ATP的生成。同时可以诱导血管扩展物体的生成。 4、过氧化物的构成 臭氧和细胞膜上脂质层的不饱满脂膏酸应变,生成过氧化氢;同时发生脂质过氧化映衬,产物包含游离氧果园、臭氧化物、碳化物、羰基、烃类、烯烃等; 5、解体噩性肿瘤 臭氧可以按捺肿瘤代谢;此外,臭氧可以氧化噩性细胞的外层脂质层,使噩性细胞崩溃,达成败坏噩性细胞的目标。臭氧击发的反噬细胞发生的过氧化氢和氢氧基可以去杀伤弧菌和毒剂。细胞形成的氢氧根对于细胞杀伤作用是分外机要的。臭氧通过鲸吞细胞可以巩固精氨酸软化为瓜氨酸亚硝酸酯和硝酸酯,上述产物均可作用与肿瘤。 6、免疫制度:臭氧能惊险身体发生α、β、γ窜扰素,白介素,肿瘤坏死因子、细胞发育因子等,从而形成接连的免疫反应; 4(应用推广情况及经济社会效益 5(其它 application; infection and antibacterial drug of clinical application; transfusion refers to levy; nutrition support of adapted card and clinical application; common life support technology (as cycle breathing support, and nutrition support,) and emergency technology of application; common guardianship instrument using. Look: shock, cardiac respiratory arrest and acute organ failure, systemic inflammatory response syndrome and severe infection and multiple organ dysfunction syndrome (MODS), severe disturbance of body fluid environment such as critical theory and progress of the illness. 2. basic requirements (1) species and cases of study requirements: severe pneumonia in disease-disease myocardial infarction ... 3. high requirements (1) learning disease species: disease species disease species image radiation: rheumatic heart congenital heart intestinal Crohn's (Crohn) disease intestinal tuberculosis bile duct cancer chronic pancreatic inflammatory urinary system stone urinary system tumor adrenal disease thyroid disease cranial within infection nervous system tumor nuclear medical: Digest road bleeding explicit like brain blood flow perfusion explicit like testicular blood pool explicit like salivary glands explicit like (2) clinical knowledge, and skills requirements: understand various image check 四、与县及国内外同类先进技术比较 ?我院针灸科成立于建院之初，为本院特色专科，针灸技术居全县首位。 ?传统康复与现代康复技术相结合是本院特色，因此在重庆区县中医院走在前列。 ?同三甲医院比，现代康复技术存在差距，但中医针灸是我们特色。整个技术有待不断搞高。 项目实施报告 五、技术成熟程序 基本成熟。 application; infection and antibacterial drug of clinical application; transfusion refers to levy; nutrition support of adapted card and clinical application; common life support technology (as cycle breathing support, and nutrition support,) and emergency technology of application; common guardianship instrument using. Look: shock, cardiac respiratory arrest and acute organ failure, systemic inflammatory response syndrome and severe infection and multiple organ dysfunction syndrome (MODS), severe disturbance of body fluid environment such as critical theory and progress of the illness. 2. basic requirements (1) species and cases of study requirements: severe pneumonia in disease-disease myocardial infarction ... 3. high requirements (1) learning disease species: disease species disease species image radiation: rheumatic heart congenital heart intestinal Crohn's (Crohn) disease intestinal tuberculosis bile duct cancer chronic pancreatic inflammatory urinary system stone urinary system tumor adrenal disease thyroid disease cranial within infection nervous system tumor nuclear medical: Digest road bleeding explicit like brain blood flow perfusion explicit like testicular blood pool explicit like salivary glands explicit like (2) clinical knowledge, and skills requirements: understand various image check 六、对社会经济发展和科技进步的意义 。 项目实施报告 七、效益 1.病例来源于城区和乡镇患者，辐射到周边区县，在该片区具有较高知名度。 2.该项目的开展填补了我院此项技术空白，同时填补在我县传统康复医学发展的空白。 application; infection and antibacterial drug of clinical application; transfusion refers to levy; nutrition support of adapted card and clinical application; common life support technology (as cycle breathing support, and nutrition support,) and emergency technology of application; common guardianship instrument using. Look: shock, cardiac respiratory arrest and acute organ failure, systemic inflammatory response syndrome and severe infection and multiple organ dysfunction syndrome (MODS), severe disturbance of body fluid environment such as critical theory and progress of the illness. 2. basic requirements (1) species and cases of study requirements: severe pneumonia in disease-disease myocardial infarction ... 3. high requirements (1) learning disease species: disease species disease species image radiation: rheumatic heart congenital heart intestinal Crohn's (Crohn) disease intestinal tuberculosis bile duct cancer chronic pancreatic inflammatory urinary system stone urinary system tumor adrenal disease thyroid disease cranial within infection nervous system tumor nuclear medical: Digest road bleeding explicit like brain blood flow perfusion explicit like testicular blood pool explicit like salivary glands explicit like (2) clinical knowledge, and skills requirements: understand various image check 八、相关的证明材料 至2012年2月开展臭氧治血疗法以来，大治血人数达1190人|次，臭氧注射关节腔达498人|次，臭氧水共计137瓶，臭氧包裹治疗4次。其中治疗中风偏瘫患者52例，类风湿关节炎患者41例，三高症患者32例，带状疱症患者11例，其他病种37例，目前总收入达366745.00万元。除去材料费12000.00万元，纯收入达246745.00万。 达 项目实施报告 九、推广应用的条件和前景 预防和治疗多种慢性疾病，起到“缓则治其本”作用。有预防疾病、保健强身的作用。“三伏贴”治病事半功倍，且老少适宜，被群众誉为无需打针吃药的绿色环保疗法。群众乐于接受。适宜推广。 application; infection and antibacterial drug of clinical application; transfusion refers to levy; nutrition support of adapted card and clinical application; common life support technology (as cycle breathing support, and nutrition support,) and emergency technology of application; common guardianship instrument using. Look: shock, cardiac respiratory arrest and acute organ failure, systemic inflammatory response syndrome and severe infection and multiple organ dysfunction syndrome (MODS), severe disturbance of body fluid environment such as critical theory and progress of the illness. 2. basic requirements (1) species and cases of study requirements: severe pneumonia in disease-disease myocardial infarction ... 3. high requirements (1) learning disease species: disease species disease species image radiation: rheumatic heart congenital heart intestinal Crohn's (Crohn) disease intestinal tuberculosis bile duct cancer chronic pancreatic inflammatory urinary system stone urinary system tumor adrenal disease thyroid disease cranial within infection nervous system tumor nuclear medical: Digest road bleeding explicit like brain blood flow perfusion explicit like testicular blood pool explicit like salivary glands explicit like (2) clinical knowledge, and skills requirements: understand various image check 十、存在的问题和建议 总结资料不完善。有待归类管理。 application; infection and antibacterial drug of clinical application; transfusion refers to levy; nutrition support of adapted card and clinical application; common life support technology (as cycle breathing support, and nutrition support,) and emergency technology of application; common guardianship instrument using. Look: shock, cardiac respiratory arrest and acute organ failure, systemic inflammatory response syndrome and severe infection and multiple organ dysfunction syndrome (MODS), severe disturbance of body fluid environment such as critical theory and progress of the illness. 2. basic requirements (1) species and cases of study requirements: severe pneumonia in disease-disease myocardial infarction ... 3. high requirements (1) learning disease species: disease species disease species image radiation: rheumatic heart congenital heart intestinal Crohn's (Crohn) disease intestinal tuberculosis bile duct cancer chronic pancreatic inflammatory urinary system stone urinary system tumor adrenal disease thyroid disease cranial within infection nervous system tumor nuclear medical: Digest road bleeding explicit like brain blood flow perfusion explicit like testicular blood pool explicit like salivary glands explicit like (2) clinical knowledge, and skills requirements: understand various image check