FERROUS LACTATE-乳酸亚铁

FERROUS LACTATE Prepared at the 35th JECFA (1989), published in FNP 49 (1990) and in FNP 52 (1992). Metals and arsenic specifications revised at the 61st JECFA (2003). A PMTDI of 0.8 mg/kg bw for iron was established at the 35th JECFA (1989) SYNONYMS INS No. 585 DEFINITION Chemical names Ferrous lactate, iron (II) lactate, iron (II) 2-hydroxypropanoate C.A.S. number 5905-52-2 Chemical formula C6H10FeO6 · xH2O, (x = 2 or 3) Structural formula Formula weight Dihydrate: 270.02 Trihydrate: 288.03 Assay Not less than 96% on the dried basis DESCRIPTION Greenish white crystals or light green powder having a weak, characteristic smell FUNCTIONAL USES Colouring adjunct, nutrient CHARACTERISTICS IDENTIFICATION Solubility (Vol. 4) Soluble in water; practically insoluble in ethanol pH (Vol. 4) 5.0 - 6.0 (1 in 50 soln) Test for lactate (Vol. 4) Passes test Test for ferrous salts (Vol. 4) Passes test PURITY Loss on drying (Vol. 4) Not more than 18% (100o using vacuum, approx. 700 mm Hg) Sulfates (Vol. 4) Not more than 0.1% Test 0.5 g of the sample as directed in the Limited Test using 1 ml of 0.01 N sulphuric acid in the control Chlorides (Vol. 4) Not more than 0.1% Test 0.5 g of the sample as directed in the Limit Test using 1.4 ml of 0.01 N hydrochloric acid in the control. Iron (III) Not more than 0.6% Dissolve about 5 g of the sample, accurately weighed, in a mixture of 100 ml of water and 10 ml of hydrochloric acid in a 250-ml glass stoppered flask. Add 3 g of potassium iodide, shake well, and allow to stand in the dark for 5 min. Titrate liberated iodine with 0.1 N sodium thiosulfate, using starch TS as the indicator. Each ml of 0.1 N sodium thiosulfate is equivalent to 5.585 mg of iron (III). Lead (Vol. 4) Not more than 1 mg/kg Determine using an atomic absorption technique appropriate to the specified level. The selection of sample size and method of sample preparation may be based on the principles of the method described in Volume 4, “Instrumental Methods.” METHOD OF ASSAY Transfer about 2 g of the dried sample, accurately weighed, to a 100-ml volumetric flask, dilute to the mark with water and mix. Pipet 20 ml of the sample solution into a 100-ml conical flask. Add 5 ml of formic acid (85% v/v). Titrate the solution with 0.1 N potassium permanganate until it turns pink. Each ml of 0.1 N potassium permanganate is equivalent to 23.40 mg of C6H10FeO6. FERROUS LACTATE SYNONYMS DEFINITION Chemical names C.A.S. number Chemical formula Structural formula Formula weight Assay DESCRIPTION FUNCTIONAL USES CHARACTERISTICS IDENTIFICATION PURITY Iron (III) Lead (Vol. 4) METHOD OF ASSAY