氨基酸的侧链保护基团

氨基酸的侧链保护基团氨基酸侧链官能团保护基保护基结构式保护基脱除条件NHOArg95%TFA，30minPbfOHNNH2NHSOO90%TFA，30minOtBuOOAsp/P)-AcOH-NMM;Pb(PhGlu34OOHPb(PhP)-PhSiHinDCM，OAll343O10-30minOAsn/90%TFA，30-60minTrtNHGlnNH290%TFA，30-60minTrtSOHg(?);Ag(?);Tl(?);CysSHAcmSNSiClPh(SO)Ph-CH33HHF(20?);Hg(?);tBuSSiClPh(SO)Ph-CH33PRSH，BuS3SStBuOtherreducingagents0.5-1%TFAinDCM-TES(95:5)，30min;MmtSOMe3%TFA，5-10minOMe5%TFA-3%TESinDCMTmobSMeOOMe,,,NNHis50%TFAinDCM，30minTrtNHO90%TFA，30-60minBocNOHOP)(0.1eq)-PhSiHPb(Ph343Alloc(24eq)inDCM，10minNOHLys/NH2Orn1%TFAinDCM，30min;NMeHMttAcOH-TFE-DCM(1:2:7)O2%水合肼inDMF，DdeNH5-10minOSer/90%TFA，30mintBuOHOThr/TyrO1-5%TFAinDCM，2-5minTrtHONTrp90%TFA，1hBocNO