慢性阻塞性肺病血皮质醇检测意义和骨代谢关系

慢性阻塞性肺病血皮质醇检测意义和骨代谢关系 慢性阻塞性肺病血皮质醇检测意义和骨代 谢关系 6 ?<?P?J?? ?<?P?J??INFORIGNMDILTRTMNT 2008NO.24 CHINAFOREIGNMEDICALTREATMENT ???f???o ???U?J???U????(COPD)?G???E?f?????????U????,?0???????R ?p?????????????6,?l?D?????D???????P?E?????I?%???U????[1] oI?? ?????????????>??????????,???????????????????????D???????? ??[2] oI?????U?p?U?????0?m???????;,?????????????????L??oI 1?K???8???? 1.1?????D?? ?C?????????b2008??5?M??????????,???<COPD??18??, ????????2002?????U?J???U???????????G??oI??????27??,?? ?m???t???X???????X???;oI 1.2???????? g??y?D?????????????O?????????????D???y3mL,?R???y?O;g? 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(1)??1???pCOPD??????????COS???r???U???IoI?????? ?c?????<,??COPD?????????yCOS?l?????P???????0????oI?? ???T?????pCOPD???O???y?????????????(?????R???????L??, ?????????????????v,?????????U?T??[3] ,?2?????L?????X?????I ?%,?XCOPD???<?yCOS?l???8?r??????????[4] oI???????T???? ?p:COPD???O?yCOS?l?????>?0??,???L?????X???G???????? ???%,?????????????????1???X[5] oI?>???????????r?pCOPD?? ??????COS?l?????r?????IoI?N???????DCOS?s???L?????X?R ?????????????;,???D?8?r???B?5????,?????????????I?U?p?? ???1?(????????????????,???????;???r?????%???6?T??2??3 ?0oI???S,COPD???O???X?P???U?????X???;,???????UCOS?l ?????D????oI (2)??2???pCOPD??????????????,???>4???8?P,COPD?? ???8?????????D?r???U???I,??3???p?g???????F???????[???8 ?r???9oI?N???????D:g??????X???;?????X:?f???????N???r?p ?????????;?????s???X???????>3???%??????[6] ,Hudson????,?? ???X???;????COPD???k????????[7] oI?????????8?????????8?? ?X???;?w???????U????,???????w???%?????;?O?????w???y???? ?:?n?????8?r[8]oI?/?m???0?1?(???????:?noI???D?E?????p?y?? ?%???>?E???r?pCOPD???X???8?????????8?r,???X???????2?? ???????????r?????I,???????????0?2oIg??????????????????T ??:COPD???O?????9???8?????G????10min????????????,???? ?????R?9?p0.71??0.51,???8?????????????????T???????;?4?? ??????[9] oIg????????;?D?y?f????o6?%????,?????????????:oI (3)??4?yCOS?l??????????????????,COS?l??????,???? ?:?n???8?roICOS?8?4???????????????????M,???v?4???????? ?J?U,???C?????????4oI?????v?????%?v,?????b???????????m 14CHAEECAEAE :tP0.0 INFORIGNMDILTRTMNT?<?P?J?? 2008NO.24 CHINAFOREIGNMEDICALTREATMENT ???f???o 1?l???K?? 1.1???>?K?? ???O,???U,65??,??????o6????o6????o6?L??????3h?l???4 3?S????oI???O3h???X???;?<???m????o6????o6?L???????????1o6?? ??o6???????4????????3?S,?????F??,???????u?V,???????????m,?? ???O?D???b?????F???????;,???????????p?s???y??????,?????O?0?? ???)???l20mL,?L???????0?A???8?n??????2008??1?M22??04:00 ?6???C??????oI???O?D???b??o6???y??o6??????o6??????o6?????U?C ????o6???X???m????oI 1.2?l?????? ????????:???-?0??,?y?????0?o,?D?.23?S/min,???%18?S/ minoI???6????,?????U??,????????,???G????,??????,?????n??,?? ?????%????,?t????????????,????25?S/min,???0??,????????,?t ?????w??,????,?????T?????h?U,????????,???u???????n?P???p,?? ?r???T?t????,???T????????,???????y???p15.7mmol/L,???a???p S?o6S?o6avFo6ST???A???C?L??????0.10??0.20mv,S????b???;???J??, S?o6avLo6V2 -V6 o6ST???l???T????0.10??0.20mv,?y?%???????? 16??109 /L,?<?U????90%,???????????p?h?U,????????548.77U/ L,a-???6???n?:??355.97U/LoI 2?????8???? 2.1???? (1)?/?U?T??????????;S????b???;???J??o6killip??????S???;(2) ?/?U????????????S????b???;???J??1?? ???B (?????6???????1?????<?J??????????663100) o4????oC?1?????C?????v????1???/?U??????????S????;???J?????O???l???????????? ?????????U?R???2???????????????2?p?l?? ????????????oI o4???c??oC?/?U????????S????b???;???l?????????? o4?<???R????oCR541o4???c?G???6oCAo4?????P??oC1674-0742(2008)08(c)-0147-01 ???y??S???,????????;(3)???????b??;(4)?????U?C????;(5)???8o6?? ?8???X???moI 2.2???? ?????8????????o6????o6???y?.??o6?????????????M????2?? ?8,???O???????n?T??,???a?????0???%,?H????T?????0????,???O?L ?????????noI?w????oI 3???? ?C???v?????????/?U????????????S????b???;???J?????O,???? ?/,????????,???????0????,?7??????oI?????O??????o6????o6?U??o6 ????o6?L??????o6???????4o6???a???k???p????????,?J???????s?? ?????????????????p?????????y??????,?????????0??,???O???O?D?? ?b??????????????????,??????????????,?Z?????p,?????8?????0?8 ?roI?X75%??95%???/?U???????????O?<24h?????A?????????n?%, ?????U?????n?%???1,???????b???;???J???????s?;???J???????8?? ???N??????,?????/??,?????????O?????R?p??????????,?????????6 ???.??????????????????,?i?????????U,?-?.?????p?y?N??,?????F ?R?/???????n?%,?b???????F????????,?i???7??[1] oI ???N???c [1]???n??,????.??????[M].?)??:???C???m?????r,2001:189?? 193. o4?v?b???moC2008-06-03 ??????,?????????U???i??????????????,COS??????????PTH ???R???2?p???l??????,???????%?voI???1??COS?????v?????R ?????U?????;,???v?????R???????;o6???%?R?????%??,???L?? ?R???????????????:?I????,???????;???????????%?v,?????; ???p???????4oI?2?>???????B?????L???????0?d,?N???E?????? ???C?D??,???S?????????O???;???X???.o6???X?????????????? ?X???;?????D??,???????????????E???V?>??oI ???N???c [1]?<???J???1???%?????1?R?1???U?J???U??????????.???U?J ???U???????????G??[J].?<?????%?????%???w??,2002,25: 453??460. 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